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M6524

盐酸甲氧明 盐酸盐

α1-adrenoceptor agonist

别名:

α-(1--氨基乙基)-2,5-二甲氧基苄醇 盐酸盐

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关于此项目

经验公式（希尔记法）:
C11H17NO3 · HCl
化学文摘社编号:
61-16-5
分子量:
247.72
NACRES:
NA.77
PubChem Substance ID:
24277785
UNSPSC Code:
12352116
EC Number:
200-499-7
MDL number:
MFCD00058607
Quality level:
200
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产品名称

盐酸甲氧明 盐酸盐,

Quality Level

200

storage temp.

2-8°C

SMILES string

Cl[H].COc1ccc(OC)c(c1)C(O)C(C)N

InChI

1S/C11H17NO3.ClH/c1-7(12)11(13)9-6-8(14-2)4-5-10(9)15-3;/h4-7,11,13H,12H2,1-3H3;1H

InChI key

YGRFXPCHZBRUKP-UHFFFAOYSA-N

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

Biochem/physiol Actions

α1-肾上腺素能受体激动剂。

Features and Benefits

该化合物在受体分类和信号转导手册中α-肾上腺素能受体页面中进行了详细介绍。想要浏览手册的其他页面， 请单击此处。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000551532
0000546758
0000526209
0000526209
0000546758

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商品

α1-Adrenoceptor Characteristics and Modulators

Review alpha 1 adrenoceptors as well as their agonists, antagonists, and tissue expression patterns. We suggest several modulators and alternatives for working with a-1 adrenoreceptors.

Sven Francque et al.
Laboratory investigation; a journal of technical methods and pathology, 92(10), 1428-1439 (2012-08-15)
Non-alcoholic fatty liver disease can progress to steatohepatitis and fibrosis, and is also associated with impaired liver regeneration. The pathophysiology remains elusive. We recently showed that severe steatosis is associated with an increase in portal pressure, suggesting liver flow impairment.
L Nalos et al.
British journal of pharmacology, 165(2), 467-478 (2011-07-02)
Drug development requires the testing of new chemical entities for adverse effects. For cardiac safety screening, improved assays are urgently needed. Isolated adult cardiomyocytes (CM) and human embryonic stem cell-derived cardiomyocytes (hESC-CM) could be used to identify pro-arrhythmic compounds. In
Chandana B Herath et al.
American journal of physiology. Gastrointestinal and liver physiology, 304(1), G99-108 (2012-10-23)
Recent studies have shown that, in cirrhosis, portal angiotensin-(1-7) [Ang-(1-7)] levels are increased and hepatic expression of angiotensin converting enzyme 2 (ACE2) and the Mas receptor are upregulated, but the effects of Ang-(1-7) on hepatic hemodynamics in cirrhosis have not
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全球贸易项目编号

货号GTIN
M6524-500MG04061834061007
M6524-1G04061834060994