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M6524

盐酸甲氧明 盐酸盐

α1-adrenoceptor agonist

别名:

α-(1--氨基乙基)-2,5-二甲氧基苄醇 盐酸盐

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关于此项目

经验公式（希尔记法）:
C11H17NO3 · HCl
化学文摘社编号:
61-16-5
分子量:
247.72
NACRES:
NA.77
PubChem Substance ID:
24277785
UNSPSC Code:
12352116
EC Number:
200-499-7
MDL number:
MFCD00058607
Quality level:
200
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产品名称

盐酸甲氧明 盐酸盐,

Quality Level

200

storage temp.

2-8°C

SMILES string

Cl[H].COc1ccc(OC)c(c1)C(O)C(C)N

InChI

1S/C11H17NO3.ClH/c1-7(12)11(13)9-6-8(14-2)4-5-10(9)15-3;/h4-7,11,13H,12H2,1-3H3;1H

InChI key

YGRFXPCHZBRUKP-UHFFFAOYSA-N

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

Biochem/physiol Actions

α1-肾上腺素能受体激动剂。

Features and Benefits

该化合物在受体分类和信号转导手册中α-肾上腺素能受体页面中进行了详细介绍。想要浏览手册的其他页面， 请单击此处。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000551532
0000546758
0000526209
0000526209
0000546758

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商品

α1-Adrenoceptor Characteristics and Modulators

Review alpha 1 adrenoceptors as well as their agonists, antagonists, and tissue expression patterns. We suggest several modulators and alternatives for working with a-1 adrenoreceptors.

Sven Francque et al.
Laboratory investigation; a journal of technical methods and pathology, 92(10), 1428-1439 (2012-08-15)
Non-alcoholic fatty liver disease can progress to steatohepatitis and fibrosis, and is also associated with impaired liver regeneration. The pathophysiology remains elusive. We recently showed that severe steatosis is associated with an increase in portal pressure, suggesting liver flow impairment.
Manuel Hernández-Guerra et al.
Hepatology (Baltimore, Md.), 57(4), 1564-1574 (2012-11-24)
Chronic intermittent hypoxia (CIH) occurs with obstructive sleep apnea syndrome (OSAS) and provokes systemic endothelial dysfunction, which is associated with oxidative stress and low nitric oxide (NO) bioavailability. Cirrhotic livers exhibit intrahepatic endothelial dysfunction, which is characterized by an impaired
Robert H Thiele et al.
Anesthesia and analgesia, 113(2), 284-296 (2011-04-27)
Phenylephrine and methoxamine are direct-acting, predominantly α(1) adrenergic receptor (AR) agonists. To better understand their physiologic effects, we screened 463 articles on the basis of PubMed searches of "methoxamine" and "phenylephrine" (limited to human, randomized studies published in English), as
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全球贸易项目编号

货号GTIN
M6524-500MG04061834061007
M6524-1G04061834060994