所有图片(2)

文件

M6635

N-(2-巯基丙酰基)甘氨酸

Name: <I>N</I>-(2-巯基丙酰基)甘氨酸
Brand: SIGMA

登录查看公司和协议定价

所有图片(2)

别名:

硫普罗宁

线性分子式:

CH₃CH(SH)CONHCH₂COOH

CAS号:

1953-02-2

分子量:

163.19

Beilstein:

1859822

EC 号:

217-778-4

MDL编号:

MFCD00004861

eCl@ss:

32160406

PubChem化学物质编号:

24897101

NACRES:

NA.26

检测方案

≥98% (TLC)

形式

powder

颜色

white

mp

98-100 °C

application(s)

cell analysis
peptide synthesis

SMILES string

CC(S)C(=O)NCC(O)=O

InChI

1S/C5H9NO3S/c1-3(10)5(9)6-2-4(7)8/h3,10H,2H2,1H3,(H,6,9)(H,7,8)

InChI key

YTGJWQPHMWSCST-UHFFFAOYSA-N

正在寻找类似产品? Visit 产品对比指南

应用

N-(2-巯丙酰)甘氨酸或Tiopronin已用于：

制备聚乙烯亚胺(PEI)包覆金微粒(PEI-gold)，进行核酸生物传递
研究活性氧(ROS)在异氟醚预处理诱导的体内神经保护中的再灌注期作用
作为ROS抑制剂，研究其对溶血磷脂酰胆碱(LPC)诱导的炎症小体激活的影响

生化/生理作用

N-(2-巯丙酰)甘氨酸(NMPG)是一种与自身免疫性低血糖相关的硫醇化合物。它是一种可扩散抗氧化剂，可降低结肠损伤的严重程度。NMPG还可减轻髓过氧化物酶活性，刺激缺氧诱导因子-1(HIF-1)-血管内皮生长因子(VEGF)溃疡愈合途径。

N-(2-巯基丙酰基)-甘氨酸是一种自由基清除剂。

象形图

GHS07

警示用语：

Warning

危险声明

H302

预防措施声明

P264 - P270 - P301 + P312 - P501

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

分析证书(COA)

输入产品批号来搜索分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

为方便起见，与您过往购买产品相关的文件已保存在文档库中。

访问文档库

难以找到您所需的产品或批次号码？

如何查找产品货号

在网站页面上，产品编号会附带包装尺寸/数量一起显示（例如：T1503-25G）。请确保在“产品编号”字段中仅输入产品编号 (示例: T1503).

示例

T1503

货号

25G

包装规格/数量

其它示例：

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

输入内容 1.000309185)

遇到问题？欢迎随时联系我们技术服务寻求帮助

如何查找COA批号

批号可以在产品标签上"批“ （Lot或Batch）字后面找到。

Aldrich 产品

如果您查询到的批号为 TO09019TO 等，请输入去除前两位字母的批号：09019TO。
如果您查询到的批号含有填充代码（例如05427ES-021），请输入去除填充代码-021的批号：05427ES。
如果您查询到的批号含有填充代码（例如 STBB0728K9），请输入去除填充代码K9的批号：STBB0728。

未找到您寻找的产品？

部分情况下，可能未在线提供COA。如果搜索不到COA，可在线索取。

索取COA

Role of reactive oxygen species at reperfusion stage in isoflurane preconditioning-induced neuroprotection.

Sang Hyun Lee et al.

Brain research, 1723, 146405-146405 (2019-08-28)

In this in vivo and in vitro study, we aimed to investigate whether isoflurane preconditioning-induced neuronal protection is mediated by reactive oxygen species (ROS) signaling at the reperfusion stage. In the in vivo study, Sprague-Dawley rats were subjected to middle

Mechanism of Emulsified Isoflurane Postconditioning-Induced Activation of the Nrf2-Antioxidant Response Element Signaling Pathway During Myocardial Ischemia-Reperfusion: The Relationship With Reactive Oxygen Species.

Wei Chen et al.

Journal of cardiovascular pharmacology, 73(5), 265-271 (2019-05-15)

Emulsified isoflurane (EI) has been shown to alleviate myocardial ischemia-reperfusion (IR) injury. However, previous reports have not been focused on the underlying mechanism. We used models of IR injury in Langendorff-isolated rat hearts to determine the relationship between the mechanism

Pyritinol

Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions, 2988-2989 (2006)

N-(2-Mercaptopropionyl)-glycine, a diffusible antioxidant, activates HIF-1 by inhibiting HIF prolyl hydroxylase-2: implication in amelioration of rat colitis by the antioxidant.

Soohwan Yum et al.

Biochemical and biophysical research communications, 443(3), 1008-1013 (2013-12-24)

We investigated anti-colitic effects of N-(2-mercaptopropionyl)-glycine (NMPG), a diffusible antioxidant, in TNBS-induced rat colitis model and a potential molecular mechanism underlying the pharmacologic effect of the antioxidant. NMPG alleviated colonic injury and effectively lowered myeloperoxidase activity. Moreover, NMPG substantially attenuated

Neoplastic cell response to tiopronin-coated gold nanoparticles.

Lei Cui et al.

Nanomedicine : nanotechnology, biology, and medicine, 9(2), 264-273 (2012-06-13)

The present study characterized the in vitro biological response of a comprehensive set of cancer cell lines to gold nanoparticles (2.7 nm) coated with tiopronin (AuNPs-TP). Our findings suggest that upon entering cells, the AuNPs-TP are sequestered in vacuoles such

查看所有相关文献

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门

文件