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Merck
CN

M6891

光辉霉素 A 来源于褶皱链霉菌

≥90% (HPLC), DNA and RNA polymerase inhibitor

别名:

普卡霉素, 金霉酸

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关于此项目

经验公式(希尔记法):
C52H76O24
化学文摘社编号:
分子量:
1085.15
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12161501
MDL number:
Beilstein/REAXYS Number:
5236667
Assay:
≥90% (HPLC)
Quality level:
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产品名称

光辉霉素 A 来源于褶皱链霉菌, ≥90% (HPLC)

Quality Level

assay

≥90% (HPLC)

antibiotic activity spectrum

neoplastics

mode of action

DNA synthesis | interferes

storage temp.

2-8°C

SMILES string

[H][C@]1(Cc2cc3cc(O[C@H]4C[C@@H](O[C@H]5C[C@@H](O)[C@H](O)[C@@H](C)O5)[C@@H](O)[C@@H](C)O4)c(C)c(O)c3c(O)c2C(=O)[C@H]1O[C@H]6C[C@@H](O[C@H]7C[C@@H](O[C@H]8C[C@](C)(O)[C@H](O)[C@@H](C)O8)[C@H](O)[C@@H](C)O7)[C@H](O)[C@@H](C)O6)[C@H](OC)C(=O)[C@@H](O)[C@@H](C)O

InChI

1S/C52H76O24/c1-18-29(72-34-14-30(43(58)21(4)68-34)73-33-13-28(54)42(57)20(3)67-33)12-26-10-25-11-27(49(66-9)48(63)41(56)19(2)53)50(47(62)39(25)46(61)38(26)40(18)55)76-36-16-31(44(59)23(6)70-36)74-35-15-32(45(60)22(5)69-35)75-37-17-52(8,65)51(64)24(7)71-37/h10,12,19-24,27-28,30-37,41-45,49-51,53-61,64-65H,11,13-17H2,1-9H3/t19-,20-,21-,22-,23-,24-,27+,28-,30-,31-,32-,33+,34+,35+,36+,37+,41+,42-,43+,44-,45-,49+,50+,51-,52+/m1/s1

InChI key

CFCUWKMKBJTWLW-BGLFSJPPSA-N

General description

Chemical structure: aureolic acid

Biochem/physiol Actions

抗癌抗生素。
抗癌抗生素。抑制转录和蛋白质合成。与天然染色质中的 DNA 结合。MDR 表型的 Pgp 底物。

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

新产品

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商品

Discover Bioactive Small Molecules for ADME/Tox

全球贸易项目编号

货号GTIN
M6891-5MG04061833264065
M6891-1MG04061834061397

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