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经验公式(希尔记法):
C15H15NO2S
化学文摘社编号:
分子量:
273.35
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
产品名称
Modafinil, ≥98% (HPLC)
SMILES string
NC(=O)CS(=O)C(c1ccccc1)c2ccccc2
InChI
1S/C15H15NO2S/c16-14(17)11-19(18)15(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10,15H,11H2,(H2,16,17)
InChI key
YFGHCGITMMYXAQ-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
solid
drug control
USDEA Schedule IV; Új pszichoaktív anyag / New psychoactive substance (Hungary), 78/2022. (XII. 28.) BM rendelet
color
white
solubility
DMSO: >10 mg/mL
originator
Teva
Quality Level
Gene Information
human ... SLC6A3(6531)
rat ... Slc6a3(24898)
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Biochem/physiol Actions
Modafinil is a central nervous system vigilance promoting agent, which posseses neuroprotective properties.
Features and Benefits
This compound was developed by Teva. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Repr. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
监管及禁止进口产品
此项目有
Kousuke Okimura et al.
Scientific reports, 11(1), 1843-1843 (2021-01-21)
At high latitudes, approximately 10% of people suffer from depression during the winter season, a phenomenon known as seasonal affective disorder (SAD). Shortened photoperiod and/or light intensity during winter season are risk factors for SAD, and bright light therapy is
Perrin Kwek et al.
European journal of pharmacology, 699(1-3), 132-140 (2012-12-12)
Modafinil is a wakefulness-promoting agent with possible beneficial effects for the management of addiction and in psychiatric conditions, but also with abuse potential of its own. The mechanism of action of modafinil remains unclear. We studied pharmacological mechanisms in the
K M Baradhi et al.
Transplantation proceedings, 45(2), 845-847 (2013-03-19)
Acute interstitial nephritis is a well-recognized cause of acute kidney injury in native kidneys. While the most common etiology being drug-induced, other causes are infectious, autoimmune, and idiopathic forms of disease. Drug-induced acute interstitial nephritis is not only uncommon in
Modafinil and armodafinil in schizophrenia.
Chittaranjan Andrade
The Journal of clinical psychiatry, 73(8), e1062-e1064 (2012-09-13)
Eduardo Prado et al.
American journal of Alzheimer's disease and other dementias, 27(7), 468-473 (2012-08-16)
Dementia with Lewy bodies (DLB) is commonly associated with excessive daytime somnolence (EDS). Modafinil is a wakefulness-promoting agent that is considered to have limited interaction with the dopaminergic system. As individuals with DLB are predisposed to psychotic symptoms that might
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