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Merck
CN

M6940

Sigma-Aldrich

Modafinil

≥98% (HPLC), Neuroprotective agent, solid

别名:

2-[(Diphenylmethyl)sulfinyl]­acetamide

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关于此项目

经验公式(希尔记法):
C15H15NO2S
化学文摘社编号:
分子量:
273.35
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
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产品名称

Modafinil, ≥98% (HPLC)

质量水平

方案

≥98% (HPLC)

表单

solid

药品控制

USDEA Schedule IV; Új pszichoaktív anyag / New psychoactive substance (Hungary), 78/2022. (XII. 28.) BM rendelet

颜色

white

溶解性

DMSO: >10 mg/mL

创始人

Teva

SMILES字符串

NC(=O)CS(=O)C(c1ccccc1)c2ccccc2

InChI

1S/C15H15NO2S/c16-14(17)11-19(18)15(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10,15H,11H2,(H2,16,17)

InChI key

YFGHCGITMMYXAQ-UHFFFAOYSA-N

基因信息

human ... SLC6A3(6531)
rat ... Slc6a3(24898)

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生化/生理作用

Modafinil is a central nervous system vigilance promoting agent, which posseses neuroprotective properties.

特点和优势

This compound was developed by Teva. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

象形图

Health hazardExclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral - Repr. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Kousuke Okimura et al.
Scientific reports, 11(1), 1843-1843 (2021-01-21)
At high latitudes, approximately 10% of people suffer from depression during the winter season, a phenomenon known as seasonal affective disorder (SAD). Shortened photoperiod and/or light intensity during winter season are risk factors for SAD, and bright light therapy is
Eduardo Prado et al.
American journal of Alzheimer's disease and other dementias, 27(7), 468-473 (2012-08-16)
Dementia with Lewy bodies (DLB) is commonly associated with excessive daytime somnolence (EDS). Modafinil is a wakefulness-promoting agent that is considered to have limited interaction with the dopaminergic system. As individuals with DLB are predisposed to psychotic symptoms that might
K M Baradhi et al.
Transplantation proceedings, 45(2), 845-847 (2013-03-19)
Acute interstitial nephritis is a well-recognized cause of acute kidney injury in native kidneys. While the most common etiology being drug-induced, other causes are infectious, autoimmune, and idiopathic forms of disease. Drug-induced acute interstitial nephritis is not only uncommon in
Perrin Kwek et al.
European journal of pharmacology, 699(1-3), 132-140 (2012-12-12)
Modafinil is a wakefulness-promoting agent with possible beneficial effects for the management of addiction and in psychiatric conditions, but also with abuse potential of its own. The mechanism of action of modafinil remains unclear. We studied pharmacological mechanisms in the
Tristan Shuman et al.
Behavioural brain research, 235(2), 105-112 (2012-09-12)
Modafinil is a wake-promoting drug effective at enhancing alertness and attention with a variety of approved and off-label applications. The mechanism of modafinil is not well understood but initial studies indicated a limited abuse potential. A number of recent publications

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