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经验公式(希尔记法):
C15H15NO2S
化学文摘社编号:
分子量:
273.35
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
产品名称
Modafinil, ≥98% (HPLC)
SMILES string
NC(=O)CS(=O)C(c1ccccc1)c2ccccc2
InChI
1S/C15H15NO2S/c16-14(17)11-19(18)15(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10,15H,11H2,(H2,16,17)
InChI key
YFGHCGITMMYXAQ-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
solid
drug control
USDEA Schedule IV; Új pszichoaktív anyag / New psychoactive substance (Hungary), 78/2022. (XII. 28.) BM rendelet
color
white
solubility
DMSO: >10 mg/mL
originator
Teva
Quality Level
Gene Information
human ... SLC6A3(6531)
rat ... Slc6a3(24898)
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Biochem/physiol Actions
Modafinil is a central nervous system vigilance promoting agent, which posseses neuroprotective properties.
Features and Benefits
This compound was developed by Teva. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Repr. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
监管及禁止进口产品
此项目有
Kousuke Okimura et al.
Scientific reports, 11(1), 1843-1843 (2021-01-21)
At high latitudes, approximately 10% of people suffer from depression during the winter season, a phenomenon known as seasonal affective disorder (SAD). Shortened photoperiod and/or light intensity during winter season are risk factors for SAD, and bright light therapy is
Modafinil #259.
Jennifer Cheng et al.
Journal of palliative medicine, 15(12), 1388-1389 (2012-12-05)
Chris Neale et al.
British journal of clinical pharmacology, 75(3), 728-737 (2012-10-10)
Over recent years there has been increasing research into both pharmaceutical and nutraceutical cognition enhancers. Here we aimed to calculate the effect sizes of positive cognitive effect of the pharmaceutical modafinil in order to benchmark the effect of two widely
Jared Bruce et al.
Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology, 25(3), 107-114 (2012-09-11)
Examine the efficacy of armodafinil in improving cognition in patients with multiple sclerosis (MS). Many patients with MS experience cognitive difficulties. Armodafinil has shown promise as a cognitive enhancer in other patient populations. No studies have examined whether armodafinil improves
Mei-Hong Qiu et al.
PloS one, 7(9), e45471-e45471 (2012-10-03)
We have previously shown that modafinil promotes wakefulness via dopamine receptor D(1) and D(2) receptors; however, the locus where dopamine acts has not been identified. We proposed that the nucleus accumbens (NAc) that receives the ventral tegmental area dopamine inputs
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