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Merck
CN

M6940

Modafinil

≥98% (HPLC), Neuroprotective agent, solid

别名:

2-[(Diphenylmethyl)sulfinyl]­acetamide

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关于此项目

经验公式(希尔记法):
C15H15NO2S
化学文摘社编号:
分子量:
273.35
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
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产品名称

Modafinil, ≥98% (HPLC)

SMILES string

NC(=O)CS(=O)C(c1ccccc1)c2ccccc2

InChI

1S/C15H15NO2S/c16-14(17)11-19(18)15(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10,15H,11H2,(H2,16,17)

InChI key

YFGHCGITMMYXAQ-UHFFFAOYSA-N

assay

≥98% (HPLC)

form

solid

drug control

USDEA Schedule IV; Új pszichoaktív anyag / New psychoactive substance (Hungary), 78/2022. (XII. 28.) BM rendelet

color

white

solubility

DMSO: >10 mg/mL

originator

Teva

Quality Level

Gene Information

human ... SLC6A3(6531)
rat ... Slc6a3(24898)

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Biochem/physiol Actions

Modafinil is a central nervous system vigilance promoting agent, which posseses neuroprotective properties.

Features and Benefits

This compound was developed by Teva. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Repr. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

监管及禁止进口产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Kousuke Okimura et al.
Scientific reports, 11(1), 1843-1843 (2021-01-21)
At high latitudes, approximately 10% of people suffer from depression during the winter season, a phenomenon known as seasonal affective disorder (SAD). Shortened photoperiod and/or light intensity during winter season are risk factors for SAD, and bright light therapy is
Perrin Kwek et al.
European journal of pharmacology, 699(1-3), 132-140 (2012-12-12)
Modafinil is a wakefulness-promoting agent with possible beneficial effects for the management of addiction and in psychiatric conditions, but also with abuse potential of its own. The mechanism of action of modafinil remains unclear. We studied pharmacological mechanisms in the
K M Baradhi et al.
Transplantation proceedings, 45(2), 845-847 (2013-03-19)
Acute interstitial nephritis is a well-recognized cause of acute kidney injury in native kidneys. While the most common etiology being drug-induced, other causes are infectious, autoimmune, and idiopathic forms of disease. Drug-induced acute interstitial nephritis is not only uncommon in
Modafinil and armodafinil in schizophrenia.
Chittaranjan Andrade
The Journal of clinical psychiatry, 73(8), e1062-e1064 (2012-09-13)
Eduardo Prado et al.
American journal of Alzheimer's disease and other dementias, 27(7), 468-473 (2012-08-16)
Dementia with Lewy bodies (DLB) is commonly associated with excessive daytime somnolence (EDS). Modafinil is a wakefulness-promoting agent that is considered to have limited interaction with the dopaminergic system. As individuals with DLB are predisposed to psychotic symptoms that might

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