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Merck
CN

M7523

Anti-Myosin (Skeletal) antibody produced in rabbit

whole antiserum

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IF, IHC (p)
Citations:
31
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biological source

rabbit

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

primary antibodies

clone

polyclonal

contains

15 mM sodium azide

species reactivity

human

enhanced validation

independent
Learn more about Antibody Enhanced Validation

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:20 using human or animal skeletal muscle, indirect immunofluorescence: 1:20 using human or animal sletetal muscle

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

General description

Myosin is a 480,000 dalton protein containing two identical heavy chains (200,000 daltons each) and four light chains (15,000-26,000 daltons). Myosin molecules consist of two major regions: tails (rods) and heads; they aggregate into filaments through the tail region. Multiple forms of myosin heavy chains exist for each muscle type; skeletal, cardiac, smooth and non-muscle isomyosin forms exist in different types of skeletal muscle, depending on the physiological function of the muscle.

Immunogen

whole myosin (heavy and light chains) from human skeletal muscle.

Application

Anti-Myosin (Skeletal) antibody produced in rabbit has been used in:
  • immunohistochemistry
  • immunostaining
  • western blotting
  • immunofluorescence
  • immunolocalization
  • immunocytochemistry

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunocytochemistry (1 paper)
Western Blotting (1 paper)

Biochem/physiol Actions

Specifically labels the A bands of human and animal skeletal muscle. Does not stain human smooth muscle tissue.

Analysis Note

The antiserum has been treated to remove lipoproteins.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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存储类别

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品
动植物来源生物产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Human fallopian tube: a new source of multipotent adult mesenchymal stem cells discarded in surgical procedures
Jazedje T, et al.
Journal of Translational Medicine, 7(1), 1-10 (2009)
Małgorzata Zimowska et al.
International journal of molecular sciences, 21(9) (2020-05-13)
Skeletal muscle regeneration depends on the satellite cells, which, in response to injury, activate, proliferate, and reconstruct damaged tissue. However, under certain conditions, such as large injuries or myopathies, these cells might not sufficiently support repair. Thus, other cell populations
Multipotent Stem Cells from Umbilical Cord: Cord Is Richer than Blood!
Secco M, et al.
Stem Cells, 26(1), 146-150 (2008)
Tatiana Jazedje et al.
Journal of translational medicine, 7, 46-46 (2009-06-23)
The possibility of using stem cells for regenerative medicine has opened a new field of investigation. The search for sources to obtain multipotent stem cells from discarded tissues or through non-invasive procedures is of great interest. It has been shown
Xenotransplantation of human dental pulp stem cells in xn-plateletrich-009f plasma for the treatment of xn-fullthickness-sm6g articular cartilage defects in a rabbit model
Yanasse RH, et al.
Experimental and Therapeutic Medicine, 17(6), 4344-4356 (2019)

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