产品名称
Anti-Myosin (Skeletal and Smooth) antibody produced in rabbit, whole antiserum
biological source
rabbit
conjugate
unconjugated
antibody form
whole antiserum
antibody product type
primary antibodies
clone
polyclonal
contains
15 mM sodium azide
species reactivity
animal, human
technique(s)
indirect immunofluorescence: 1:10 using cultured fibroblasts
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... MYH10(4628), MYH9(4627), MYL9(10398)
Application
Anti-Myosin (Skeletal and Smooth) antibody produced in rabbit has been used in indirect immunofluorescence labeling.
Biochem/physiol Actions
Myosin plays a vital role in neurosensory and cortical function, membrane vesicle trafficking and determinant partitioning. Myosins with actin-stimulated ATPase activity is essential for various cellular movements. Myosins I and V mediates vesicle translocation. Myosin II with a long rod like tail domain, assembles into a bipolar thick filament and facilitate muscle contraction.
Shows a pattern of staining along stress fibers of cultured human and animal fibroblasts.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Myosin is a 500 kD protein that interacts with actin in muscle and in non-muscle cells. It is characterized with two identical heavy chains (200 kD each) and four light chains (15-20 kD each). Myosin molecules consist of two major regions; the tail (rod) and head. These molecules aggregate into filaments through the tail region and interact with actin and ATP through the head region.
Immunogen
whole myosin (heavy and light chains) from bovine uterus.
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存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
动植物来源生物产品
此项目有
F Baluska et al.
Developmental biology, 227(2), 618-632 (2000-11-10)
Plant root hair formation is initiated when specialized elongating root epidermis cells (trichoblasts) assemble distinct domains at the plasma membrane/cell wall cell periphery complexes facing the root surface. These localities show accumulation of expansin and progressively transform into tip-growing root
Myosin: The Actin Motor Protein
Molecular Cell Biology, 10(1), 80-86 (2000)
Root hair formation: F-actin-dependent tip growth is initiated by local assembly of profilin-supported F-actin meshworks accumulated within expansin-enriched bulges
Baluska F, et al.
Developmental Biology, 227(2), 618-632 (2000)
Myosins: matching functions with motors.
Baker JP and Titus MA.
Current Opinion in Cell Biology, 10(1), 80-86 (1998)
Ngoc Minh Nguyen et al.
Frontiers in cell and developmental biology, 10, 992371-992371 (2022-12-20)
The evolutionary emergence of the primitive gut in Metazoa is one of the decisive events that conditioned the major evolutionary transition, leading to the origin of animal development. It is thought to have been induced by the specification of the
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