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关于此项目
经验公式(希尔记法):
C26H44O9
化学文摘社编号:
分子量:
500.62
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
920-1020 μg/mg (HPLC)
Form:
crystalline
产品名称
莫匹罗星, 920-1020 μg/mg (HPLC), crystalline
Quality Segment
assay
920-1020 μg/mg (HPLC)
form
crystalline
color
white to yellow
antibiotic activity spectrum
fungi
mode of action
enzyme | inhibits, protein synthesis | interferes
originator
GlaxoSmithKline
storage temp.
room temp
SMILES string
[H][C@@]1(CO[C@@H](C\C(C)=C\C(=O)OCCCCCCCCC(O)=O)[C@H](O)[C@@H]1O)C[C@@H]2O[C@@]2([H])[C@@H](C)[C@H](C)O
InChI
1S/C26H44O9/c1-16(13-23(30)33-11-9-7-5-4-6-8-10-22(28)29)12-20-25(32)24(31)19(15-34-20)14-21-26(35-21)17(2)18(3)27/h13,17-21,24-27,31-32H,4-12,14-15H2,1-3H3,(H,28,29)/b16-13+/t17-,18-,19-,20-,21-,24+,25-,26-/m0/s1
InChI key
MINDHVHHQZYEEK-HBBNESRFSA-N
General description
Mupirocin is produced by Pseudomonas fluorescens. Mupirocin is used to treat impetigo and skin infections.
Application
Mupirocin has been used:
- for kinetic assay
- to assess its resistance by performing turbidity assay
- to determine its antimicrobial susceptibility
Biochem/physiol Actions
Antibiotic; inhibits isoleucyl-tRNA synthetase (IRS).
Features and Benefits
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Preparation Note
Mupirocin is poorly soluble in water (26 mg/L), but highly soluble in DMSO (≥10 mg/mL). If sterilization is required, it is advisable to use filter sterilization with a 0.22 µm PTFE, Polypropylene, or Nylon filter membrane.
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存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)