M7765
1-油酰基-rac-甘油
≥99%
别名:
MG(18:1(9Z)/0:0/0:0)[rac], 1-(顺-9- 十八烯酰基)-rac-甘油, rac-甘油 1-单油酸酯, DL-α-甘油单油酸酯, 甘油顺-9-十八烯酰基, 甘油单油酸酯
生物来源
synthetic (organic)
描述
non-ionic
方案
≥99%
表单
powder
mp
35 °C
官能团
ester
脂质类型
neutral glycerides
运输
wet ice
储存温度
−20°C
SMILES字符串
O=C(CCCCCCC/C=C\CCCCCCCC)OCC(O)CO
InChI
1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-
InChI key
RZRNAYUHWVFMIP-KTKRTIGZSA-N
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一般描述
1-油酰基-rac-甘油是一种甘油单酸酯，获取自天然油脂。它包含两个活性醇基。它可溶于氯仿和己烷。它可从己烷中结晶。
应用
1-油酰基-rac-甘油已用于：
- 通过两针法与样品混合，利用结晶技术中获得脂质立方相
- 用作单酸甘油酯（MG）脂肪酶测定的底物
- 制备用于测定MG水解酶体外活性的MG溶液
生化/生理作用
1-油酰基-rac-甘油对脂蛋白脂肪酶介导的甘油三酸酯水解同时呈现抑制和抗抑制作用。
甘油单油酸酯（1-油酰-rac-甘油）被用来研发基于甘油单油酸酯的纳米颗粒液体分散剂，作为潜在的给药载体。
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
309.2 °F - closed cup
闪点(°C)
154.0 °C - closed cup
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Tuo Zhang et al.
Science advances, 3(8), e1700344-e1700344 (2017-09-07)
Zrt/Irt-like proteins (ZIPs) play fundamental roles in metal metabolism/homeostasis and are broadly involved in numerous physiological and pathological processes. The lack of high-resolution structure of the ZIPs hinders understanding of the metal transport mechanism. We report two crystal structures of
Recent Advances in Environmentally Compatible Polymers: Cellucon?99 Proceedings, 205-205 (2001)
Liron Bitan-Cherbakovsky et al.
The journal of physical chemistry. B, 115(42), 11984-11992 (2011-09-10)
The incorporation of dendrimer into three lyotropic liquid crystalline (LLCs) mesophases is demonstrated for the first time. A second generation (G2) of poly(propylene imine) dendrimer (PPI) was solubilized into lamellar, diamond reverse cubic, and reverse hexagonal LLCs composed of glycerol
Biophysical effects of monoglycerides in membrane systems, 16-16 (1995)
Elisabetta Esposito et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 80(2), 306-314 (2011-11-09)
The physico-chemical properties and in vivo efficacies of two nanoparticulate systems delivering the antiparkinsonian drug bromocriptine (BC) were compared in the present study. Monoolein Aqueous Dispersions (MADs) and Nanostructured Lipid Carriers (NLCs) were produced and characterized. Cryogenic transmission electron microscopy
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