M8046
米非司酮
synthetic (organic), ≥98%, Progesterone receptor antagonist, powder
别名:
11β-（4-二甲基-氨基）-苯基17β-羟基-17-（1-丙炔基）-雌甾-4,9-三胺-3-酮, RU-38486, RU-486
选择尺寸
关于此项目
产品名称
米非司酮, ≥98%
SMILES string
[H][C@@]12CCC3=CC(=O)CCC3=C1[C@H](C[C@@]4(C)[C@@]2([H])CC[C@@]4(O)C#CC)c5ccc(cc5)N(C)C
InChI
1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1
InChI key
VKHAHZOOUSRJNA-GCNJZUOMSA-N
biological source
synthetic (organic)
sterility
non-sterile
assay
≥98%
form
powder
technique(s)
inhibition assay: suitable
solubility
ethanol: 50 mg/mL, clear, greenish-yellow
originator
Danco Laboratories
shipped in
ambient
storage temp.
2-8°C
Gene Information
human ... AR(367), ESR1(2099), ESR2(2100), HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363), NR3C1(2908), NR3C2(4306), PGR(5241)
mouse ... Nr3c1(14815)
rat ... Nr3c1(24413), Tat(24813)
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相关类别
Application
- 诱导破坏增殖和分泌期的子宫内膜基质细胞
- 建立小鼠早产(PTB)模型，研究非早产和PTB宫颈成熟机制的差异
- 激活果蝇基因开关gal4
- 研究性类固醇对于前列腺素分泌的影响
Biochem/physiol Actions
Features and Benefits
General description
hcodes
signalword
Danger
pcodes
Hazard Classifications
Repr. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
What is Mifepristone, Product M8046, soluble in?
Mifepristone is soluble in ethanol at 50 mg/mL; heat may be required to dissolve the compound at this concentration. It is also soluble in DMSO at 20 mg/mL.
Can solutions of Mifepristone, Product M8046, be stored?
Stock solutions of 1 mM mifepristone in ethanol can be stored at -20 °C. The top of the container should be sealed with Parafilm to prevent solvent evaporation. Solutions in ethanol, properly stored and handled, are probably good for several months (based on the structure of the compound), but we have no specific information on this.
Where can I find information on usage of Mifepristone, Product M8046?
The Sigma-Aldrich website listing has several cited articles with hyperlinks to the abstracts. These references can be found under the reference tab on the M8046 product webpage.
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
My question is not addressed here, how can I contact Technical Service for assistance?
Ask a Scientist here.
相关内容
Product Information Sheet
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