M8069
Monoclonal Anti-Mad1 antibody produced in mouse
~2 mg/mL, clone 9B10, purified immunoglobulin, buffered aqueous solution
别名:
Anti-Mitotic Arrest Deficient
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关于此项目
Conjugate:
unconjugated
Clone:
9B10, monoclonal
Application:
ARR, ICC, IP
Citations:
6
biological source
mouse
Quality Segment
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
9B10, monoclonal
form
buffered aqueous solution
mol wt
antigen ~85 kDa
species reactivity
human
concentration
~2 mg/mL
technique(s)
immunocytochemistry: 10-20 μg/mL using HeLa cells, immunoprecipitation (IP): suitable, microarray: suitable
isotype
IgG2b
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... MAD1L1(8379)
General description
Mitotic arrest deficient-like 1 (MAD1) is part of the cell-cycle checkpoint.
Monoclonal Anti-Mad1 (mouse IgG2b isotype) is derived from the hybridoma 9B10 produced by the fusion of mouse myeloma cells (SP2/0 cells) and splenocytes from BALB/c mice immunized with human recombinant Mad1 protein.
Immunogen
recombinant human Mad1 protein.
Application
Monoclonal Anti-Mad1 antibody produced in mouse has been used in
- immunoblotting
- immunoprecipitation
- immunocytochemistry
Biochem/physiol Actions
Mitotic arrest deficient-like 1 (MAD1) functions as a regulator in the segregation of chromosomes during mitosis. It recruits mitotic arrest deficient-like 2 (MAD2) to kinetochores and directs it to function as an inhibitor. MAD1 also helps MAD2 to associate with translocated promoter region (TPr).
Physical form
Solution in 0.01 M phosphae buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable