M8692
Anti-Matrix Metalloproteinase-21, Hinge Region antibody produced in rabbit
affinity isolated antibody, buffered aqueous glycerol solution
别名:
Anti-MMP-21
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous glycerol solution
种属反应性
rat, human, Xenopus, mouse
技术
western blot: 1:1,000
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... MMP21(118856)
mouse ... Ighg(380794)
一般描述
Matrix metalloproteinase-21 (MMP-21) is a secreted protein expressed in fetal tissues, adult tissues and cancer cell lines. It is a 57kDa protein. The gene encoding it is localized on human chromosome 10.
免疫原
synthetic peptide corresponding to the hinge region of human matrix metalloproteinase-21.
生化/生理作用
By immunoblotting against the reduced protein, the antibody identifies bands at 70 kDa and 66 kDa.
Matrix metalloproteinase-21 (MMP-21) is involved in increasing the invasion capacity and metastasis property of tumors.
外形
Solution in 0.01 M phosphate buffered saline containing 50% glycerol and 0.05% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
法规信息
新产品
Raja Ganesan et al.
PLoS pathogens, 13(2), e1006227-e1006227 (2017-02-14)
During intracellular infections, autophagy significantly contributes to the elimination of pathogens, regulation of pro-inflammatory signaling, secretion of immune mediators and in coordinating the adaptive immune system. Intracellular pathogens such as S. Typhimurium have evolved mechanisms to circumvent autophagy. However, the
Katja Ahokas et al.
Gene, 301(1-2), 31-41 (2002-12-20)
We have characterized a novel human matrix metalloproteinase (MMP-21) from human placenta DNA complementary to RNA (cDNA). The 569 amino acid translation of the cDNA includes all the typical features of an MMP family member, namely a signal sequence, a
Tiina Skoog et al.
Experimental dermatology, 15(10), 775-783 (2006-09-21)
Matrix metalloproteinase (MMP)-21 and MMP-26 (matrilysin-2) are two recently cloned epithelial metalloproteases. Here we examined their expression in various benign skin disorders, in which macrophages and fibroblasts have been implicated as well as in cultures of these cells. Expression of
Tao Wu et al.
Medical oncology (Northwood, London, England), 30(1), 323-323 (2013-01-01)
Matrix metalloproteinase-21 (MMP-21) has been shown to enhance tumor invasion and metastasis ability in some solid tumors. In the present study, we investigated the expression of MMP-21 as well as its association with overall survival of gastric cancer patients. MMP-21
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