生物来源
Monkey (Cynomolgus spp.)
表单
liquid
比活
≥5000 units/mg protein
包装
vial of ~10 mg
运输
dry ice
储存温度
−70°C
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应用
Microsomes from Liver, Pooled has been used to measure the in vitro stabilities of the prodrugs. It has also been used in microsomal incubation to generate BTX-3 metabolites to serve as references for liquid chromatography with tandem mass spectrometry (LC-MS/MS) analyses of urine.
生化/生理作用
肝微粒体是来源于肝细胞内质网的亚细胞颗粒。这些微粒体是药物代谢酶(包括细胞色素 P-450)的丰富来源。不同来源的微粒体池有助于研究外源代谢和药物相互作用。
药物代谢酶的来源,包括细胞色素 P-450。
Microsomal cytochrome P450 proteins can catalyze the transfer of a single oxygen atom to endogenous and exogenous compounds, like steroids and phenobarbital, meant for excretion and detoxification.
单位定义
One unit will produce 1.0 picomole of 6 beta-hydroxytestosterone per minute at pH 7.4 at 37 deg C.
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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