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Merck
CN

M9005

3-甲基-L-组氨酸

≥98% (TLC)

别名:

π-甲基-L-组氨酸, 1-甲基-L-组氨酸(不再使用), 3-(1-甲基咪唑-5-基)-L丙氨酸

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关于此项目

经验公式(希尔记法):
C7H11N3O2
化学文摘社编号:
分子量:
169.18
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26
EC Number:
206-704-6
MDL number:
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产品名称

3-甲基-L-组氨酸,

assay

≥98% (TLC)

Quality Level

form

powder

color

white to off-white

mp

254 °C

application(s)

detection

SMILES string

Cn1cncc1C[C@H](N)C(O)=O

InChI

1S/C7H11N3O2/c1-10-4-9-3-5(10)2-6(8)7(11)12/h3-4,6H,2,8H2,1H3,(H,11,12)/t6-/m0/s1

InChI key

JDHILDINMRGULE-LURJTMIESA-N

Application


  • Engineering mutually orthogonal PylRS/tRNA pairs for dual encoding of functional histidine analogues.:研究创新基因工程技术,用组氨酸类似物(如3-甲基-L-组氨酸)制出功能改进的新蛋白。治疗和工业应用前景广阔(Taylor et al., 2023)。

  • Improving the enzymatic activity of l-amino acid α-ligase for imidazole dipeptide production by site-directed mutagenesis.:研究如何改进咪唑二肽的酶促合成。对于了解各种修饰(如3-甲基-L-组氨酸)的作用及其生物活性影响有重要意义(Kino et al., 2023)。

Biochem/physiol Actions

3-甲基-L-组氨酸是一种非蛋白原氨基酸,也是一项肌肉分解的指标。

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M N Goodman
The American journal of physiology, 260(5 Pt 1), E727-E730 (1991-05-01)
The metabolic response to infection includes loss of lean tissue and increased nitrogen excretion. The loss of muscle tissue during infection results in large part from accelerated skeletal muscle protein breakdown. Recent studies suggest that macrophage-derived products secreted during infection
E Roth et al.
Clinical chemistry, 31(8), 1305-1309 (1985-08-01)
We measured amino acid concentrations in plasma and skeletal muscle of three groups of patients with acute hemorrhagic pancreatitis: (a) patients without secondary organ lesions, (b) patients also suffering from kidney damage, and (c) patients in whom the pancreatitis was
Melanie J Edwards et al.
Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 180(2), 247-257 (2009-09-04)
We fed common brushtail possums artificial diets containing a buffer and the plant secondary metabolite (PSM), orcinol, to test the hypothesis that organic acids, common products of PSM metabolism, limit feeding by common brushtail possums (Trichosurus vulpecula). We introduced several
M Hansen et al.
Scandinavian journal of medicine & science in sports, 21(1), 62-72 (2009-11-04)
Oral contraceptive (OC) treatment has an inhibiting effect on protein synthesis in tendon and muscle connective tissue. We aimed to investigate whether OC influence myofibrillar protein turnover in young women. OC-users (24±2 years; Lindynette® n=7, Cilest® n=4) and non-OC-users (controls
Elin Chorell et al.
Journal of proteome research, 8(6), 2966-2977 (2009-03-26)
We have investigated whether postexercise ingestion of carbohydrates in combination with proteins generates a different systemic metabolic response, as compared to the sole ingestion of carbohydrate or water, in the early recovery phase following exercise. In addition, metabolic patterns related

全球贸易项目编号

货号GTIN
M9005-1G04061826061008
M9005-250MG04061832417578
M9005-100MG04061834063803

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