M9005
3-甲基-L-组氨酸
≥98% (TLC)
别名:
π-甲基-L-组氨酸, 1-甲基-L-组氨酸（不再使用）, 3-（1-甲基咪唑-5-基）-L丙氨酸
产品名称
3-甲基-L-组氨酸,
方案
≥98% (TLC)
质量水平
表单
powder
颜色
white to off-white
mp
254 °C
应用
detection
SMILES字符串
Cn1cncc1C[C@H](N)C(O)=O
InChI
1S/C7H11N3O2/c1-10-4-9-3-5(10)2-6(8)7(11)12/h3-4,6H,2,8H2,1H3,(H,11,12)/t6-/m0/s1
InChI key
JDHILDINMRGULE-LURJTMIESA-N
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应用
- Engineering mutually orthogonal PylRS/tRNA pairs for dual encoding of functional histidine analogues.：研究创新基因工程技术，用组氨酸类似物（如3-甲基-L-组氨酸）制出功能改进的新蛋白。治疗和工业应用前景广阔(Taylor et al., 2023)。
- Improving the enzymatic activity of l-amino acid α-ligase for imidazole dipeptide production by site-directed mutagenesis.：研究如何改进咪唑二肽的酶促合成。对于了解各种修饰（如3-甲基-L-组氨酸）的作用及其生物活性影响有重要意义(Kino et al., 2023)。
生化/生理作用
3-甲基-L-组氨酸是一种非蛋白原氨基酸，也是一项肌肉分解的指标。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
E Roth et al.
Clinical chemistry, 31(8), 1305-1309 (1985-08-01)
We measured amino acid concentrations in plasma and skeletal muscle of three groups of patients with acute hemorrhagic pancreatitis: (a) patients without secondary organ lesions, (b) patients also suffering from kidney damage, and (c) patients in whom the pancreatitis was
M N Goodman
The American journal of physiology, 260(5 Pt 1), E727-E730 (1991-05-01)
The metabolic response to infection includes loss of lean tissue and increased nitrogen excretion. The loss of muscle tissue during infection results in large part from accelerated skeletal muscle protein breakdown. Recent studies suggest that macrophage-derived products secreted during infection
M Hansen et al.
Scandinavian journal of medicine & science in sports, 21(1), 62-72 (2009-11-04)
Oral contraceptive (OC) treatment has an inhibiting effect on protein synthesis in tendon and muscle connective tissue. We aimed to investigate whether OC influence myofibrillar protein turnover in young women. OC-users (24±2 years; Lindynette® n=7, Cilest® n=4) and non-OC-users (controls
S G A van der Drift et al.
Journal of dairy science, 95(9), 4911-4920 (2012-08-25)
The objective of this study was to obtain information on variation between dairy cows in muscle and fat tissue mobilization around parturition and to study the association between protein and fat mobilization and serum β-hydroxybutyrate (BHBA) concentrations (hyperketonemia) in this
Richard Lee et al.
Analytical chemistry, 82(7), 2959-2968 (2010-03-03)
Despite several decades of active research, the success of large-scale clinical trials involving antioxidants remains equivocal given the complex biological interactions of reactive oxygen/nitrogen species in human health. Herein, we outline a differential metabolomics strategy by capillary electrophoresis-electrospray ionization-mass spectrometry
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