M9005
3-甲基-L-组氨酸
≥98% (TLC)
别名:
π-甲基-L-组氨酸, 1-甲基-L-组氨酸（不再使用）, 3-（1-甲基咪唑-5-基）-L丙氨酸
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关于此项目
经验公式（希尔记法）:
C7H11N3O2
化学文摘社编号:
分子量:
169.18
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26
EC Number:
206-704-6
MDL number:
产品名称
3-甲基-L-组氨酸,
assay
≥98% (TLC)
Quality Level
form
powder
color
white to off-white
mp
254 °C
application(s)
detection
SMILES string
Cn1cncc1C[C@H](N)C(O)=O
InChI
1S/C7H11N3O2/c1-10-4-9-3-5(10)2-6(8)7(11)12/h3-4,6H,2,8H2,1H3,(H,11,12)/t6-/m0/s1
InChI key
JDHILDINMRGULE-LURJTMIESA-N
Application
- Engineering mutually orthogonal PylRS/tRNA pairs for dual encoding of functional histidine analogues.：研究创新基因工程技术，用组氨酸类似物（如3-甲基-L-组氨酸）制出功能改进的新蛋白。治疗和工业应用前景广阔(Taylor et al., 2023)。
- Improving the enzymatic activity of l-amino acid α-ligase for imidazole dipeptide production by site-directed mutagenesis.：研究如何改进咪唑二肽的酶促合成。对于了解各种修饰（如3-甲基-L-组氨酸）的作用及其生物活性影响有重要意义(Kino et al., 2023)。
Biochem/physiol Actions
3-甲基-L-组氨酸是一种非蛋白原氨基酸，也是一项肌肉分解的指标。
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
M N Goodman
The American journal of physiology, 260(5 Pt 1), E727-E730 (1991-05-01)
The metabolic response to infection includes loss of lean tissue and increased nitrogen excretion. The loss of muscle tissue during infection results in large part from accelerated skeletal muscle protein breakdown. Recent studies suggest that macrophage-derived products secreted during infection
E Roth et al.
Clinical chemistry, 31(8), 1305-1309 (1985-08-01)
We measured amino acid concentrations in plasma and skeletal muscle of three groups of patients with acute hemorrhagic pancreatitis: (a) patients without secondary organ lesions, (b) patients also suffering from kidney damage, and (c) patients in whom the pancreatitis was
M Houweling et al.
Journal of dairy science, 95(6), 3125-3130 (2012-05-23)
To improve monitoring of protein mobilization in dairy cows, we developed and evaluated a method to quantify 1-methylhistidine and 3-methylhistidine in plasma by HPLC-tandem mass spectrometry. The analytical method described is (1) sensitive: both histidine derivates can be detected in
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| M9005-1G | 04061826061008 |
| M9005-250MG | 04061832417578 |
| M9005-100MG | 04061834063803 |