产品名称
Anti-Macrophage Inflammatory Protein-3β antibody produced in goat, affinity isolated antibody, lyophilized powder
biological source
goat
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
mouse
technique(s)
immunocytochemistry: 5-15 μg/mL
neutralization: 0.8-4 μg/mL
western blot: 0.1 μg/mL
UniProt accession no.
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
mouse ... Ccl19(24047)
Biochem/physiol Actions
Macrophage Inflammatory Protein-3β is a chemokine that facilitates the migration of dendritic cells and antigen-presenting cells. It interacts with specific G protein-coupled seven-transmembrane domain chemokine receptor, CCR7 and promotes interactions between T cells and dendritic cells and migration of activated B cells to lymphoid tissues.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
The antibody neutralizes the biological activity of recombinant mouse MIP-3β. Using 50 times more, the antibody will neutralize the biological activity of recombinant human MIP-3β. The antibody shows 5% cross-reactivity with recombinant human MIP-3β.
Immunogen
Recombinant mouse MIP-3β, expressed in Escherichia coli.
Physical form
Lyophilized from 0.2 um-filtered solution in phosphate buffered saline, pH 7.4 with 5% Trehalose
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存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Jian-mei Hou et al.
Acta pharmacologica Sinica, 30(3), 355-363 (2009-03-06)
Tumor immunotherapy aims at activating the body's own immune system to fight an existing tumor. Effective antitumor responses require tumor antigens to be presented to lymphocytes. We aimed to test the hypothesis that intratumoral administration of recombinant adenovirus encoding MIP3beta
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