M9651
马普替林 盐酸盐
>99% (HPLC), powder
别名:
9-(γ-Methylaminopropyl)-9,10-dihydro-9,10-ethanoanthracene hydrochloride
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关于此项目
经验公式（希尔记法）:
C20H23N · HCl
化学文摘社编号:
分子量:
313.86
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
233-758-8
MDL number:
Assay:
>99% (HPLC)
Form:
powder
Quality Segment
assay
>99% (HPLC)
form
powder
color
white
solubility
H2O: 50 mg/mL
originator
Novartis
SMILES string
Cl.CNCCCC12CCC(c3ccccc13)c4ccccc24
InChI
1S/C20H23N.ClH/c1-21-14-6-12-20-13-11-15(16-7-2-4-9-18(16)20)17-8-3-5-10-19(17)20;/h2-5,7-10,15,21H,6,11-14H2,1H3;1H
InChI key
NZDMFGKECODQRY-UHFFFAOYSA-N
Gene Information
human ... SLC6A2(6530)
Application
Maprotiline hydrochloride has been used as a inhibitor of norepinephrine uptake to study its effects on arresting L3055 cell proliferation.
Biochem/physiol Actions
Maprotiline is a tetracyclic agent. It possesses inhibitory effects against the uptake of norepinephrine by nerve cells. Maprotiline exhibits anti-depressant and sedative activity.
Features and Benefits
This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
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