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About This Item
经验公式(希尔记法):
C20H23N · HCl
CAS Number:
分子量:
313.86
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
质量水平
方案
>99% (HPLC)
表单
powder
颜色
white
溶解性
H2O: 50 mg/mL
创始人
Novartis
SMILES字符串
Cl.CNCCCC12CCC(c3ccccc13)c4ccccc24
InChI
1S/C20H23N.ClH/c1-21-14-6-12-20-13-11-15(16-7-2-4-9-18(16)20)17-8-3-5-10-19(17)20;/h2-5,7-10,15,21H,6,11-14H2,1H3;1H
InChI key
NZDMFGKECODQRY-UHFFFAOYSA-N
基因信息
human ... SLC6A2(6530)
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应用
Maprotiline hydrochloride has been used as a inhibitor of norepinephrine uptake to study its effects on arresting L3055 cell proliferation.
生化/生理作用
Maprotiline is a tetracyclic agent. It possesses inhibitory effects against the uptake of norepinephrine by nerve cells. Maprotiline exhibits anti-depressant and sedative activity.
特点和优势
This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
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