usage
sufficient for 100 colorimetric tests
application(s)
cosmetics
food and beverages
detection method
colorimetric
relevant disease(s)
neurological disorders; cancer
storage temp.
−20°C
General description
谷氨酸是两种酸性蛋白原氨基酸之一，也是细胞代谢中的关键分子。由谷氨酸脱氢酶从谷氨酸中合成α-KG是TCA循环中关键的厌氧反应。在人体中，谷氨酸在氨基酸降解和处理过量或废氮中都起着重要作用。在哺乳动物神经系统中，谷氨酸是最丰富的兴奋性神经递质。它被认为与学习和记忆有关，也可能与肌萎缩侧索硬化、自闭症、某些形式的精神发育迟滞、以及阿尔茨海默症#8242;等疾病有关。谷氨酸存在于各种食品中，并已用作食品工业中的增味剂。
Application
其适用于对各种样品中的谷氨酸浓度进行测定。
谷氨酸测定试剂盒已用于测定大鼠蛛网膜下腔出血模型中脑脊液中谷氨酸的浓度。其还被用于确定肌萎缩侧索硬化患者脑脊液中细胞溶质的和分泌的谷氨酸浓度。
Biochem/physiol Actions
谷氨酸浓度通过偶联酶测定法进行测定，其能够产生与样品中存在的谷氨酸盐成比例的比色（450nm）产物。
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
法规信息
低风险生物材料
此项目有
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Mishra P S, et al.
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Phototherapy was introduced in the early 1950's, and is the primary treatment of severe neonatal jaundice or Crigler-Najjar syndrome. Nevertheless, the potential biological effects of the products generated from the photodegradation of bilirubin during phototherapy remain unknown. This is very
Glutamate, at the interface between amino acid and carbohydrate metabolism.
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The Journal of Nutrition, 130(4), 988S-990S (2000)
Glutamate as a neurotransmitter in the healthy brain.
Zhou Y and Danbolt N C
Journal of Neural Transmission. General Section, 121(8), 799-817 (2014)
商品
Sigma article discusses tumor cell metabolic pathways, focusing on aerobic glycolysis and mitochondrial activity.
本文介绍了增殖活性细胞为何需要碳源和氮源合成大分子。尽管大部分肿瘤细胞利用有氧糖酵解途径并分流线粒体氧化磷酸化代谢物，但许多肿瘤细胞表现出线粒体活性增加。
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