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Merck
CN

MAK036

血红素检测试剂盒

sufficient for 100 colorimetric tests

别名:

氯化血红素定量检测试剂盒

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关于此项目

NACRES:
NA.84
UNSPSC Code:
12161503
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usage

sufficient for 100 colorimetric tests

application(s)

cosmetics
food and beverages

detection method

colorimetric

relevant disease(s)

immunological diseases; rheumatological diseases; gastrointestinal diseases; cardiovascular diseases

storage temp.

2-8°C

General description

作为血红素的氧化形式,氯高铁血红素是一种含有多种蛋白质的含铁修复基团。在溶血后从血红蛋白中释放出来的游离血红素具有促炎性,有助于铁源活性氧的生成。游离血红素水平可在多种病理条件下上调,并可导致多种炎性病症,包括血管病症、肾衰竭和免疫介导的病症。

Application

氯高铁血红素测定试剂盒长期用于测定游离氯高铁血红素(氧化血红素)的水平。
适合用于细胞和组织培养上清液、尿液、血浆、血清、粪便材料、培养基和其他生物样品。

Biochem/physiol Actions

在该测定中,通过偶联的酶反应测定血红素浓度,其产生与存在的 Hemin 成比例的比色(570nm)产物。

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1

存储类别

10 - Combustible liquids

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup

法规信息

动植物源性产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Kelly A Fader et al.
Toxicology and applied pharmacology, 321, 1-17 (2017-02-19)
Persistent aryl hydrocarbon receptor (AhR) agonists elicit dose-dependent hepatic lipid accumulation, oxidative stress, inflammation, and fibrosis in mice. Iron (Fe) promotes AhR-mediated oxidative stress by catalyzing reactive oxygen species (ROS) production. To further characterize the role of Fe in AhR-mediated
Guangjian Yang et al.
Open life sciences, 16(1), 930-936 (2021-09-24)
Immunoglobulin γ-1 heavy chain constant region (IGHG1) is a functional isoform of immunoglobulins and plays an important role in the cytolytic activity of immune effector cells. Dysregulated IGHG1 was implicated in the occurrence and development of various tumors. Protoporphyrin IX
Convergence of hepcidin deficiency, systemic iron overloading, heme accumulation, and REV-ERBα/β activation in aryl hydrocarbon receptor-elicited hepatotoxicity.
Fader K A, et al.
Toxicology and Applied Pharmacology, 321, 1-17 (2017)
Laura Casares et al.
Redox biology, 28, 101321-101321 (2019-09-14)
Cannabidiol (CBD) is a major non-psychotropic phytocannabinoid that attracted a great attention for its therapeutic potential against different pathologies including skin diseases. However, although the efficacy in preclinical models and the clinical benefits of CBD in humans have been extensively
Characterization of novel inhibition of indoleamine 2, 3-dioxygenase by targeting its apo form.
Ortiz-Meoz R F, et al.
bioRxiv, 324947-324947 (2018)

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