Merck
CN

MAK043

Sigma-Aldrich

胆固醇定量试剂盒

sufficient for 100 colorimetric or fluorometric tests

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别名:
胆固醇检测试剂盒
NACRES:
NA.25

用途

sufficient for 100 colorimetric or fluorometric tests

检测方法

colorimetric
fluorometric

相关疾病

cancer; cardiovascular diseases

储存温度

−20°C

一般描述

胆固醇是哺乳动物细胞膜的重要组成部分,它在细胞内运输、细胞信号传导和维持细胞膜流动性方面发挥作用。在血液中,胆固醇以游离酸和胆固醇酯的形式循环。控制血清胆固醇水平具有重要的治疗作用,因为胆固醇水平升高与动脉粥样硬化和心血管疾病的发展有关。近来的证据表明,胆固醇稳态的紊乱有助于慢性炎症状态的发展。

胆固醇主要由肝脏产生。胆固醇水平异常与冠心病有关。胆固醇与乳腺癌的进展或抑制有关。肿瘤细胞能够合成它们自己的胆固醇,这有助于细胞增殖。在癌症中观察到胆固醇水平的升高,尤其是在前列腺癌中。肥胖症或者中观察到胆固醇升高。

应用

胆固醇定量试剂盒已可用于测定血清总胆固醇水平。

适用性

适用于细胞和组织培养样品、尿液、血浆、血清等生物样品。

原理

胆固醇定量试剂盒还可用于测定样品中游离胆固醇、胆固醇酯或两者(总)的浓度。在该试剂盒中,总胆固醇浓度由耦合酶测定法测定,其结果为比色法(570 nm)/荧光法(λex = 535/λem = 587 nm)产物,与胆固醇含量成正比。

象形图

Health hazard

警示用语:

Danger

危险声明

危险分类

Resp. Sens. 1 - Skin Sens. 1

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

188.6 °F - closed cup

闪点(°C)

87 °C - closed cup

法规信息

常规特殊物品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

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示例

T1503
货号
-
25G
包装规格/数量

其它示例:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

输入内容 1.000309185)

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批号可以在产品标签上"批“ (Lot或Batch)字后面找到。

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  • 如果您查询到的批号为 TO09019TO 等,请输入去除前两位字母的批号:09019TO。

  • 如果您查询到的批号含有填充代码(例如05427ES-021),请输入去除填充代码-021的批号:05427ES。

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索取COA

  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. Can these kits be used with serum samples from mouse?

    Yes, this kit can be used on mouse serum samples. We generally recommend that fresh serum samples be used. Frozen samples can probably be used. However, the successful use of frozen samples depends on the efficiency of freezing them and the amount of time they have been frozen. If previously frozen serum samples are used, you may want to check the performance of the kit with fresh vs. frozen samples.

  6. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Cholesterol and Cancer, in the Balance.
Sandrine S P and Poirot M
Science, 343(6178), 1445-1446 (2014)
Mingzhi Han et al.
EMBO molecular medicine, 12(1), e10924-e10924 (2019-11-30)
Dysregulated cholesterol metabolism is a hallmark of many cancers, including glioblastoma (GBM), but its role in disease progression is not well understood. Here, we identified cholesterol 24-hydroxylase (CYP46A1), a brain-specific enzyme responsible for the elimination of cholesterol through the conversion
Hypolipidemic and Anti-Atherogenic Activity of Aqueous Extract of Leaves of Lagenaria siceraria in Wistar Rats.
Aslam M and Nijam R
Journal of Natural Remedies, 14(1), 52-57 (2013)
Time trends in population cholesterol levels 1986--2004: influence of lipid-lowering drugs, obesity, smoking and educational level. The northern Sweden MONICA study
Eliasson M, et al.
J. Int. Med., 260(6), 551-559 (2006)
Is There Any Relationship between Diabetic Gastroparesis and Mucosal Injury?
Cakir O O.
J Gastrointest Dig Syst , 6(461), 2-2 (2016)

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