用途
sufficient for 100 colorimetric tests
检测方法
colorimetric
相关疾病
gastrointestinal diseases; cardiovascular diseases
储存温度
−20°C
基因信息
human ... GOT1(2805)
mouse ... GOT1(14718)
rat ... GOT1(24401)
一般描述
现在我们可提供全新的天冬氨酸转氨酶检测试剂盒MAK467！天冬氨酸转氨酶（AST），以前被称为血清谷草转氨酶（SGOT），是一种吡哆醛磷酸盐（PLP）依赖酶，催化天冬氨酸和α-酮戊二酸转化成草酰乙酸和谷氨酸。和丙氨酸转氨酶（ALT）类似，血液中AST水平通常作为肝功能标记物。但是，AST分布的器官范围比ALT要广，AST水平的变化可能是疾病或多性器官损伤引起，包括骨骼和心脏。
应用
AST活性分析试剂盒可以用来检测样本中天冬氨酸转氨酶活性。
适用于测量组织、细胞和血清等各种生物样品中的天冬氨酸转氨酶（AST）活性。
生化/生理作用
天冬氨酸转氨酶活性分析试剂盒提供简单和直接的方法，用于检测各种样本中的AST活性。在该试剂盒中，天冬氨酸上的氨基基团转移到α酮戊二酸上，生成谷氨酸，生成的比色（450nm）产物和AST酶活性成正比。一单位的AST是37℃，pH8.0，生成 1.0 μmole的谷氨酸的酶当量。
特点和优势
兼容高通量处理系统。
警示用语：
Danger
危险声明
危险分类
Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B
储存分类代码
8A - Combustible corrosive hazardous materials
法规信息
低风险生物材料
此项目有
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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PloS one, 11(3), e0151765-e0151765 (2016-03-22)
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Kuang H, et al.
Oncology Reports, 35, 307-317 (2016)
Xinyi Xu et al.
Microbiology (Reading, England), 161(6), 1219-1230 (2015-03-27)
Aspartate and glutamate are two key amino acids used in biosynthesis of many amino acids that play vital role in cellular metabolism. Aspartate aminotransferases (AspATs) are required for channelling nitrogen (N(2)) between Glu and Asp in all life forms. Biochemical
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Journal of cellular biochemistry, 119(9), 7397-7405 (2018-05-19)
Liver ischemia/reperfusion (I/R) injury has high mortality due to the intense inflammatory process occurs in the liver. However, the pathological mechanism underlying I/R injury is still not clear. Recent works showed that circular RNAs play critical roles in many human
Muthukumaran Jayachandran et al.
European journal of pharmacology, 829, 112-120 (2018-04-18)
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