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Merck
CN

MAK057

柠檬酸检测试剂盒

sufficient for 100 colorimetric or fluorometric tests

别名:

柠檬酸测试试剂盒

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关于此项目

NACRES:
NA.84
UNSPSC Code:
12161503
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usage

sufficient for 100 colorimetric or fluorometric tests

application(s)

cosmetics
food and beverages

detection method

colorimetric, fluorometric

relevant disease(s)

cancer

storage temp.

−20°C

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General description

柠檬酸是三羧酸(TCA)循环的关键中间体,通过向乙酰辅酶A的乙酰基中加入草酰乙酸而得。柠檬酸通过柠檬酸-苹果酸梭子从线粒体中转运出来,然后转化回乙酰辅酶A进行脂肪酸合成。柠檬酸是脂肪酸合成和糖酵解的别构调节剂,分别通过作用于乙酰辅酶A羧化酶和磷酸果糖激酶来实现。由于性别、年龄和各种其他因素(包括疾病状态),柠檬酸的代谢和分布差异可能很大。前列腺癌细胞中的细胞柠檬酸水平降低,柠檬酸水平可能是前列腺癌生长速率的标志物。柠檬酸检测试剂盒提供了一种可简单、灵敏、快速地对各种样品中的柠檬酸进行定量的方法。

Application

柠檬酸检测试剂盒用于检测样品中柠檬酸的浓度。
适用于对包括组织和细胞在内的多种样品中的柠檬酸盐进行测定

Biochem/physiol Actions

柠檬酸的浓度通过酶偶联法检测,产生与存在的柠檬酸成比例的比色(570 nm)/荧光(λex = 535/λem = 587 nm)产物。柠檬酸检测试剂盒的灵敏度在各种样品中通常为0.1至10 nM(2 μmM-10 mM)柠檬酸。

hcodes

Hazard Classifications

Aquatic Chronic 3

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup

法规信息

监管及禁止进口产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Nimrit Goraya et al.
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Acid (H+) retention appears to contribute to progressive decline in glomerular filtration rate (GFR) in patients with chronic kidney disease (CKD), including some patients without metabolic acidosis. Identification of patients with H+ retention but without metabolic acidosis could facilitate targeted
Jade D Bailey et al.
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Classical activation of macrophages (M(LPS+IFNγ)) elicits the expression of inducible nitric oxide synthase (iNOS), generating large amounts of NO and inhibiting mitochondrial respiration. Upregulation of glycolysis and a disrupted tricarboxylic acid (TCA) cycle underpin this switch to a pro-inflammatory phenotype.
Cheng Zhang et al.
Cell reports, 21(8), 2058-2065 (2017-11-23)
We discovered that induced pluripotent stem cell (iPSC) clones generated from aged tissue donors (A-iPSCs) fail to suppress oxidative phosphorylation. Compared to embryonic stem cells (ESCs) and iPSCs generated from young donors (Y-iPSCs), A-iPSCs show poor expression of the pluripotent
Yan Huang et al.
Regenerative biomaterials, 7(2), 221-232 (2020-04-17)
The purpose of this article was to explore the effects of gold nanoparticles (GNPs) and silver nanoparticles (SNPs) with different cytotoxicities on human dermal fibroblasts (HDFs) at the metabolic level. First, ∼20 nm of GNPs and SNPs were prepared, and their
Nishikant Wase et al.
Plant physiology, 174(4), 2146-2165 (2017-06-28)
Microalgae are proposed as feedstock organisms useful for producing biofuels and coproducts. However, several limitations must be overcome before algae-based production is economically feasible. Among these is the ability to induce lipid accumulation and storage without affecting biomass yield. To

商品

Fatty acid synthesis supports cancer cell proliferation, essential for membrane generation, protein modification, and bioenergetics.

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