usage
sufficient for 100 colorimetric or fluorometric tests
species reactivity
mouse, human
storage condition
dry at room temperature
technique(s)
activity assay: suitable
input
blood
cell
accession no.
P00338, NC_000011.10, NC_000073.7
application(s)
cosmetics
food and beverages
detection method
colorimetric, fluorometric
relevant disease(s)
endocrinological disorders, diabetes; cancer
storage temp.
−20°C
Gene Information
human ... LDHA(3939)
mouse ... Ldha(16828)
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General description
L(+)-乳酸是一种通过乳酸脱氢酶的作用而在动物中形成的代谢化合物。乳酸是在增殖的细胞中以及在诸如运动的无氧条件下产生的。 异常高浓度的乳酸与癌症、糖尿病和乳酸酸中毒等病理状况有关。L(+)-乳酸是在人体中间代谢中所形成的乳酸的主要立体异构体，并以约1-2 mmol/L的水平存在于血液中。该试剂盒可提供一种简便的方法用于在生物学样本中进行L(+)-乳酸的检测。无需对样本进行预处理或纯化。
Application
乳酸检测试剂盒已用于确定样本中乳酸的浓度。
适合用于在培养基、发酵培养基、血液和细胞中检测L(+)-乳酸。
Biochem/physiol Actions
在该测定中，乳酸的浓度是通过一种酶检测而被测定的，其可产生与存在的乳酸成比例的比色（570nm）/荧光测定（λex = 535 nm/λem = 587 nm）产物。该试剂盒的常见灵敏度水平在0.001-10 mM之间。
signalword
Danger
存储类别
10 - Combustible liquids
flash_point_f
188.6 °F - closed cup
flash_point_c
87 °C - closed cup
wgk
WGK 2
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
法规信息
动植物源性产品
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Warburg effect enhances glucose to lactate conversion in tumor cells, regardless of oxygen levels; impacting cancer metabolism since 1924.
本页面介绍了一篇有关瓦博格效应的文章，以及其如何能够在正常氧气水平下，增强肿瘤细胞中葡萄糖向乳酸的转化。Otto Heinrich Warburg在1924年证明，癌细胞显示出对糖酵解的依赖性增加，以满足他们的能量需求，无论是否有充足的氧气存在。
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