用途
sufficient for 500 colorimetric tests
种属反应性
mouse, human
储存条件
dry at room temperature
技术
activity assay: suitable
输入
cell
tissue
登记号
P00338
NC_000011.10
NC_000073.7
检测方法
colorimetric
相关疾病
hematological disorder; cancer
储存温度
−20°C
基因信息
human ... LDHA(3939), LDHB(3945)
mouse ... LDHA(16828), LDHB(16832)
rat ... LDHA(24533), LDHB(24534)
一般描述
新型乳酸脱氢酶检测试剂盒 MAK464 现已上市！乳酸脱氢酶（LDH）是一种可催化丙酮酸和乳酸相互转化的氧化还原酶。 细胞在组织损伤或红细胞溶血后会将LDH释放到血流中。由于LDH是一种相当稳定的酶，它已被广泛用于评估组织和细胞是否存在损伤和毒性。LDH在某些特定的病理状态如癌症中会被提高。LDH的定量具有一系列不同的应用。
应用
乳酸脱氢酶活性检测试剂盒已用于在细胞培养基中对乳酸脱氢酶（LDH）的活性进行测定。
乳酸脱氢酶活性检测试剂盒已用于确定样本中乳酸脱氢酶的浓度。
乳酸脱氢酶活性检测试剂盒已用于确定样本中乳酸脱氢酶的浓度。
生化/生理作用
在该试剂盒中，LDH可将NAH还原成NADH，并通过比色（450 nm）检测而被特异性检测到。LDH活性检测试剂盒可在多种生物学样本中对LDH活性进行量化。该试剂盒快速、便捷而灵敏。
警示用语：
Danger
危险声明
危险分类
Eye Dam. 1 - Skin Corr. 1B
储存分类代码
8A - Combustible corrosive hazardous materials
法规信息
常规特殊物品
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Nanomaterials (Basel, Switzerland), 10(4) (2020-04-02)
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Chen Q, et al.
The Journal of Biological Chemistry, jbc-M115 (2015)
商品
Warburg effect enhances glucose to lactate conversion in tumor cells, regardless of oxygen levels; impacting cancer metabolism since 1924.
本页面介绍了一篇有关瓦博格效应的文章，以及其如何能够在正常氧气水平下，增强肿瘤细胞中葡萄糖向乳酸的转化。Otto Heinrich Warburg在1924年证明，癌细胞显示出对糖酵解的依赖性增加，以满足他们的能量需求，无论是否有充足的氧气存在。
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