usage
sufficient for 100 colorimetric tests
detection method
colorimetric
relevant disease(s)
cancer; gastrointestinal diseases
storage temp.
−20°C
Gene Information
human ... GLUD1(2746), GLUD2(2747)
mouse ... GLUD1(14661)
rat ... GLUD1(24399)
General description
谷氨酸脱氢酶 (GDH) 是一种线粒体酶，催化谷氨酸可逆性氧化脱氨生成 α-酮戊二酸，作为合成代谢和分解代谢途径之间的关键链接。在哺乳动物中，GDH受变构调节，在肝脏、肾脏、大脑和胰腺中具有较高的活性。血清中的 GDH 活性可用于区分肝脏炎症所致的肝脏疾病（未显示血清 GDH 活性升高）和导致肝细胞坏死的疾病（导致血清 GDH 升高）。
Application
谷氨酸脱氢酶 (GDH) 活性测定试剂盒已用于测定谷氨酸脱氢酶的酶活性。
适用于检测血清或组织及细胞提取液中的谷氨酸脱氢酶 (GDH) 活性。
Biochem/physiol Actions
通过偶联酶试验可测定 GDH 活性，其中谷氨酸被 GDH 消耗，生成 NADH，NADH 与探针反应生成与 GDH 活性成比例的比色 (450 nm) 产物。一个单位的GDH 在37℃下pH 7.6 时 每分钟将产生1.0μ摩尔NADH的酶量。
Features and Benefits
与高通量处理系统兼容。
存储类别
10 - Combustible liquids
法规信息
监管及禁止进口产品
此项目有
相关内容
Instructions
The glutamate dehydrogenase pathway and its roles in cell and tissue biology in health and disease.
Plaitakis A, et al.
Biology, 6(1), 11-11 (2017)
Is liver enzyme release really associated with cell necrosis induced by oxidant stress?.
Contreras-Zentella M L and Hernandez-Mu?oz R
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Animal nutrition (Zhongguo xu mu shou yi xue hui), 4(3), 329-337 (2018-09-04)
The liver is the most essential organ for the metabolism of ammonia, in where most of ammonia is removed by urea and glutamine synthesis. Regulated by leucine, glutamate dehydrogenase (GDH) catalyzes the reversible inter-conversion of glutamate to ammonia. To determine
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| 货号 | GTIN |
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