usage
sufficient for 200 fluorometric tests (red)
detection method
fluorometric
relevant disease(s)
neurological disorders; cancer
storage temp.
−20°C
正在寻找类似产品? 访问 产品对比指南
General description
活性氧 (ROS) 是由于有氧呼吸过程中氧气减少和细胞内各种酶系统产生的。在生理水平，活性氧有助于细胞信号和宿主防御。ROS 生成增加，高于生物系统的解毒能力，导致氧化应激和细胞损伤。对细胞的主要损伤是由 ROS 诱导的膜脂、必需蛋白质和 DNA 中的多不饱和脂肪酸等大分子的改变所致。ROS 与阿尔茨海默病、帕金森病、癌症、衰老等疾病状态有关。
Application
本试剂盒适于通过酶标仪或荧光显微镜检测细胞内的ROS。
荧光细胞内活性氧 (ROS) 试剂盒已用于检测活细胞中的细胞内 ROS。
Biochem/physiol Actions
试剂盒提供灵敏的一步荧光测定方法，不用孵育1小时即可检测活细胞的胞内 ROS(特别是超氧化物和羟基自由基)。ROS与细胞透过性传感器反应，生成的荧光产物（λex = 520/λem = 605 nm）与 ROS 量成比例。这一测定可用荧光微板读取仪，在96孔或384孔多孔板中进行。
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Reactive oxygen species (ROS) and response of antioxidants as ROS-scavengers during environmental stress in plants.
Das K and Roychoudhury A
Frontiers in Endocrinology, 2, 53-53 (2014)
Minghui Liu et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(4), 5535-5547 (2019-01-17)
Tumor suppressor phosphatase and tensin homolog deleted on chromosome 10 (PTEN) plays a critical role in regulating cell survival, cell growth, and proliferation by antagonizing the PI3K-AKT-mTOR pathway. The regulatory mechanism of PTEN protein is still not completely understood. Here
Comparative in vitro toxicity of a graphene oxide-silver nanocomposite and the pristine counterparts toward macrophages.
Luna L A V, et al.
Journal of Nanobiotechnology, 14(1), 12-12 (2016)
Jianyong Yu et al.
Experimental and therapeutic medicine, 22(3), 946-946 (2021-07-27)
Salinomycin is a polyether antiprotozoal antibiotic that is widely used as an animal food additive. Some antifungal, antiparasitic, antiviral and anti-inflammatory activities have been reported for salinomycin. Recently, the anti-cancer effect of salinomycin has been demonstrated in breast cancer; however
Yara E Elakkad et al.
Breast cancer (Dove Medical Press), 13, 675-689 (2021-12-23)
Female breast cancer is the most prevalent cancer worldwide. Emerging evidence shows that simvastatin (SIM) has promising anticancer activities. However, the underlying mechanisms are not fully elucidated. Increasing reports imply statins can modulate ferroptosis through disrupting reactive oxygen species (ROS)
相关内容
Instructions
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持