usage
sufficient for 500 fluorometric tests (red fluorescence)
detection method
fluorometric
relevant disease(s)
cardiovascular diseases; aging/geriatric diseases; orthopedic diseases; pulmonary disorders; neurological disorders
storage temp.
−20°C
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General description
过氧化氢是由分子氧代谢产生的活性氧类物质,既是一种细胞内信号传导信使,也是一种氧化应激来源。过氧化氢由细胞通过多种机制生成,如中性粒细胞和巨噬细胞内NOX介导的ROS产生(呼吸爆发),或者通过在线粒体呼吸期间由电子泄漏产生的超氧阴离子的歧化酶催化产生ROS。异常的过氧化氢产生将导致细胞氧化损伤以及哮喘、动脉粥样硬化、骨质疏松症和神经变性等疾病进展。
Application
试剂盒适用于定量分析各种样品(如细胞提取物和溶液)中的过氧化氢水平。
Biochem/physiol Actions
荧光法过氧化氢检测试剂盒提供了一种简便、可重复的定量分析各种样品中(如细胞提取物和溶液)过氧化氢水平的方法。试剂盒还可用于检测活细胞释放的过氧化氢或者由氧化酶活性产生的过氧化氢。该试剂盒利用过氧化物酶底物与过氧化氢反应,产生的红色荧光产物(λex = 540/λem = 590 nm)可用荧光酶标仪进行分析。
Features and Benefits
兼容高通量的操作系统。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Resp. Sens. 1
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
wgk
WGK 3
法规信息
动植物源性产品
此项目有
Yue Yang et al.
The Journal of biological chemistry, 294(23), 9295-9307 (2019-04-06)
Interest in pharmacological agents capable of increasing cellular NAD+ concentrations has stimulated investigations of nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN). NR and NMN require large dosages for effect. Herein, we describe synthesis of dihydronicotinamide riboside (NRH) and the discovery
Foteini Vasilopoulou et al.
GeroScience, 43(2), 965-983 (2020-11-01)
Brain aging and dementia are current problems that must be solved. The levels of imidazoline 2 receptors (I2-IRs) are increased in the brain in Alzheimer's disease (AD) and other neurodegenerative diseases. We tested the action of the specific and selective
Haijie Tong et al.
Environmental science & technology, 52(20), 11642-11651 (2018-09-21)
Reactive oxygen species (ROS) play a central role in adverse health effects of air pollutants. Respiratory deposition of fine air particulate matter can lead to the formation of ROS in epithelial lining fluid, potentially causing oxidative stress and inflammation. Secondary
Ellen E Salmon et al.
Cells, 9(5) (2020-05-28)
Clinical studies have established a connection between oxidative stress, aging, and atherogenesis. These factors contribute to senescence and inflammation in the endothelium and significant reductions in endothelium-dependent vasoreactivity in aged patients. Tissue-engineered blood vessels (TEBVs) recapitulate the structure and function
Eda Gjika et al.
ACS applied materials & interfaces, 10(11), 9269-9279 (2018-02-24)
Cold atmospheric plasma (CAP), an ionized gas operated at near-ambient temperatures, has been introduced as a new therapeutic opportunity for treating cancers. The effectiveness of the therapy has been linked to CAP-generated reactive oxygen and nitrogen species such as hydrogen
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