usage
sufficient for 400 fluorometric tests
detection method
fluorometric
storage temp.
−20°C
General description
Farnesyltransferase (FTase, EC 2.5.1.58) catalyzes the transfer of a farnesyl group from farnesylpyrophosphate to the cysteine residue of the C-terminus of target proteins. When not properly regulated, farnesylated proteins, including the Ras super family of small GTPases, can lead to developmental disorders and cancer.
Application
Suitable for the quantitative determination of FTase enzyme activity in biological samples.
Biochem/physiol Actions
In this assay, FTase reacts with farnesyl pyrophosphate and the dansyl-peptide substrate releasing a product that is measurable by fluorescence (λem/ex = 340/550 nm). The linear detection range is 0.024 – 3.2 U/LFTase.
存储类别
10 - Combustible liquids
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nwg