MSST0011
SILu™Prot ALB Albumin human
recombinant, expressed in HEK 293 cells, SIL MS Protein Standard, 13C and 15N-labeled
别名:
Albumin, LC/MS internal standard for human albumin in, stable isotope-labeled human albumin
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关于此项目
NACRES:
NA.12
UNSPSC Code:
23201100
Biological source:
human
Assay:
≥98% (SDS-PAGE)
Form:
lyophilized powder
Technique(s):
mass spectrometry (MS): suitable, protein mass spectrometry: suitable
Concentration:
≥10 μg/mg (Bradford)
biological source
human
Quality Segment
recombinant
expressed in HEK 293 cells
tag
His tagged
assay
≥98% (SDS-PAGE)
form
lyophilized powder
potency
≥98% Heavy amino acids incorporation efficiency by MS
concentration
≥10 μg/mg (Bradford)
technique(s)
mass spectrometry (MS): suitable, protein mass spectrometry: suitable
suitability
suitable for mass spectrometry (standard)
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... ALB(213)
General description
SILu™Prot ALB is a recombinant, stable isotope-labeled human albumin which incorporates [13C6, 15N4]-Arginine and [13C6, 15N2]-Lysine. Expressed in human 293 cells, it is designed to be used as an internal standard for bioanalysis of albumin in mass-spectrometry. SILu™Prot ALB is a monomer of 607 amino acids (including C-terminal polyhistidine and flag tags), with a molecular weight of ~69 kDa.
Biochem/physiol Actions
Albumin is synthesized exclusively by the liver parenchymal cells at a rate of 14 g/day. While it is the most abundant plasma protein (>50%), increased urine albumin concentrations indicate bleedings in the lower urinary tract (ureter, bladder) or infections of the renal pelvis. A small abnormal albumin excretion is known as Microalbuminuria and serves as an indicator for temporary overload of the glomerular filtration (fever, excessive sports) or chronic injury of the glomeruli (diabetes).
Physical form
Supplied as a lyophilized powder containing phosphate buffered saline.
Other Notes
RRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGLDYKDDDDKGHHHHHHHHGGQ
Legal Information
SILu is a trademark of Sigma-Aldrich Co. LLC
存储类别
11 - Combustible Solids
怎么回事？
WGK 2
闪点 (F)
Not applicable
闪点 (°C)
Not applicable