N0665
NDSB 211
≥98% (TLC)
别名:
3- [二甲基-（2-羟乙基）铵]-1-丙磺酸盐, 二甲基-2-羟乙基氨羟丙烷磺酸盐, 二甲基（2-羟乙基）（3-磺丙基）氢氧化铵内盐
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关于此项目
经验公式（希尔记法）:
C7H17NO4S
化学文摘社编号:
分子量:
211.28
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12161900
EC Number:
254-176-0
MDL number:
产品名称
NDSB 211, ≥98% (TLC)
Quality Level
InChI
1S/C7H17NO4S/c1-8(2,5-6-9)4-3-7-13(10,11)12/h9H,3-7H2,1-2H3
InChI key
CNXPCGBLGHKAIL-UHFFFAOYSA-N
SMILES string
OCC[N+](C)(C)CCCS([O-])(=O)=O
description
zwitterionic
assay
≥98% (TLC)
form
solid
mol wt
211.28 g/mol
technique(s)
DNA extraction: suitable
color
white
solubility
methanol: 5 mg/mL, clear, colorless
Application
NDSB 211 已被用于一项评估温和增溶剂非洗涤剂磺基甜菜碱对嗜盐蛋白质的稳定作用的研究。 在一项研究中也使用它来研究一种替代的大分子结晶策略。
非清洁剂磺基甜菜碱是一种用于非变性蛋白质纯化的化合物。提高膜、核及细胞骨架相关蛋白的提取率。两性离子在较宽的 pH 范围内，容易被透析清除，在近紫外范围内无明显吸收。具体应用包括微粒体蛋白提取、核蛋白回收、IEF 中沉淀还原、膜结合蛋白酶纯化等。
General description
二甲基-2-羟乙基氨膦磺酸盐或 NDSB 211 是一种非洗涤剂-磺基甜菜碱。 在较宽的 pH 范围内呈两性离子，易被透析去除，在近紫外范围内无明显吸收。
Other Notes
本品不形成胶束。
signalword
Danger
hcodes
Hazard Classifications
Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Searching for silver bullets: An alternative strategy for crystallizing macromolecules
McPhersona, A., et al.
Journal of Structural Biology, 156, 3887-3406 (2006)
L Vuillard et al.
Analytical biochemistry, 230(2), 290-294 (1995-09-20)
In this work, experiments performed on pig heart and halophilic malate dehydrogenase as well as halophilic elongation factor Tu demonstrate a protein stabilization property from the recently described mild solubilizing agents nondetergent sulfobetaines. A practical application is given by the
Ivanka M Karadzic et al.
Proteomics, 5(2), 354-359 (2005-01-04)
Proteins of haloarchaea are remarkably unstable in low-ionic-strength solvents and tend to aggregate under standard two-dimensional (2-D) gel electrophoresis conditions, causing strong horizontal streaking. We have developed a new approach to generate 2-D maps of halophilic proteins which included washing
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