Merck
CN

N0761

Sigma-Aldrich

烟酸

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, ≥98%

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别名:
3-吡啶甲酸, 吡啶-3-羧酸, 尼亚生, 抗糙皮病因子, 维生素 B3
经验公式(希尔记法):
C6H5NO2
CAS号:
分子量:
123.11
Beilstein:
109591
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.71

产品线

BioReagent

质量水平

检测方案

≥98%

形式

powder

分子量

Mw 123.11 g/mol

技术

cell culture | insect: suitable
cell culture | mammalian: suitable
cell culture | plant: suitable

颜色

white to off-white

pH值(酸碱度)

3.4 (20 °C, 10 g/L)

mp

236-239 °C (lit.)

溶解性

1 M NaOH: soluble 50 mg/mL, clear, colorless to very faintly yellow

密度

1.473 g/cm3 at 25 °C

应用

agriculture

SMILES字符串

OC(=O)c1cccnc1

InChI

1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)

InChI key

PVNIIMVLHYAWGP-UHFFFAOYSA-N

基因信息

human ... CYP1A2(1544)
rat ... Chrnb2(54239)

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象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

379.4 °F - closed cup

闪点(°C)

193 °C - closed cup

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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Beat Müller et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 20(2), 181-195 (2003-10-11)
A novel methodology for establishing a pharmacological dose-effect relationship of methyl nicotinate, hexyl nicotinate and nicotinic acid acting as peripheral vasodilators in the skin following topical application is investigated. This methodology involves the estimation of the unbound drug concentration in
Paul M Lavigne et al.
Journal of the American College of Cardiology, 61(4), 440-446 (2012-12-26)
This study sought to assess the efficacy of niacin for reducing cardiovascular disease (CVD) events, as indicated by the aggregate body of clinical trial evidence including data from the recently published AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High
Koon K Teo et al.
Stroke, 44(10), 2688-2693 (2013-07-25)
In Atherothrombosis Intervention in Metabolic Syndrome with low HDL/High Triglycerides: Impact on Global Health Outcomes (AIM-HIGH) trial, addition of extended-release niacin (ERN) to simvastatin in participants with established cardiovascular disease, low high-density lipoprotein cholesterol, and high triglycerides had no incremental
John R Guyton et al.
Journal of the American College of Cardiology, 62(17), 1580-1584 (2013-08-07)
This study sought to examine the relationship between niacin treatment, lipoproteins, and cardiovascular (CV) outcomes in this secondary analysis of the AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglycerides and Impact on Global Health Outcomes) trial. During a
Martina Lukasova et al.
Trends in pharmacological sciences, 32(12), 700-707 (2011-09-29)
Nicotinic acid (niacin) has been used for decades to prevent and treat atherosclerosis. The well-documented antiatherogenic activity is believed to result from its antidyslipidemic effects, which are accompanied by unwanted effects, especially a flush. There has been renewed interest in

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