N1514
神经酸
≥99% (capillary GC)
别名:
顺-15-二十四碳烯酸, 鲨油酸
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关于此项目
线性分子式:
CH3(CH2)7CH=CH(CH2)13COOH (cis)
化学文摘社编号:
分子量:
366.62
UNSPSC Code:
12352211
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1728551
InChI key
GWHCXVQVJPWHRF-KTKRTIGZSA-N
SMILES string
CCCCCCCC\C=C/CCCCCCCCCCCCCC(O)=O
InChI
1S/C24H46O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24(25)26/h9-10H,2-8,11-23H2,1H3,(H,25,26)/b10-9-
biological source
plant
assay
≥99% (capillary GC)
form
powder
mp
42-43 °C (lit.)
functional group
carboxylic acid
lipid type
unsaturated FAs
shipped in
ambient
storage temp.
−20°C
Quality Level
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Application
神经酸已被用作体外合成的脂质补充剂，用于研究发育饮食对果蝇寿命的影响。
Biochem/physiol Actions
神经酸（C24:1）是膜鞘脂和磷脂酰乙醇胺的成分，它可能是慢性肾病死亡率和糖尿病的有效预测因子。目前正在研究神经酸油在制药、营养品和工业中的应用。神经酸是Lunaria油的主要成分。
Packaging
密封安瓿包装。
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
Developmental diet regulates Drosophila lifespan via lipid autotoxins
Stefana MI, et al.
Nature Communications, 8(1), 1384-1384 (2017)
Y Mizushina et al.
Journal of molecular biology, 304(3), 385-395 (2000-11-25)
Unsaturated long-chain fatty acids selectively bind to the DNA binding sites of DNA polymerase beta and DNA topoisomerase II, and inhibit their activities, although the amino acid sequences of these enzymes are markedly different from each other. Computer modeling analysis
Arja T Erkkilä et al.
The Journal of craniofacial surgery, 16(5), 764-769 (2005-09-30)
The fatty acid profiles of serum lipids were examined in 53 ten-year-old cleft children. The children presented with different cleft types (cleft lip, cleft lip and palate, isolated cleft palate and submucuous cleft palate) and were recruited from the Finnish
Demetris Bitsanis et al.
The Journal of nutrition, 135(11), 2566-2571 (2005-10-28)
The aim of this study was to determine whether the high concentration of arachidonic acid (AA) in term placentae accumulates during pregnancy or is an inherent characteristic of placental lipids. We investigated the lipid content and fatty acid composition of
Jiun-Rong Chen et al.
The Journal of nutritional biochemistry, 15(8), 467-472 (2004-08-11)
Nutritional factors may be relative to attention-deficit hyperactive disorder (ADHD), although the pathogenic mechanism is still unknown. Based on the work of others, we hypothesized that children with ADHD have altered dietary patterns and fatty acid metabolism. Therefore, the aim
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