N1786
NSC 95397
≥97% (HPLC)
别名:
2,3-双[(2-羟乙基)硫代] -1,4-萘醌
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关于此项目
经验公式（希尔记法）:
C14H14O4S2
化学文摘社编号:
分子量:
310.39
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
产品名称
NSC 95397, ≥97% (HPLC)
InChI
1S/C14H14O4S2/c15-5-7-19-13-11(17)9-3-1-2-4-10(9)12(18)14(13)20-8-6-16/h1-4,15-16H,5-8H2
SMILES string
OCCSC1=C(SCCO)C(=O)c2ccccc2C1=O
InChI key
MAASHDQFQDDECQ-UHFFFAOYSA-N
assay
≥97% (HPLC)
form
powder
color
orange, solid
solubility
DMSO: 16 mg/mL
storage temp.
−20°C
Quality Level
Gene Information
human ... CDC25A(993), CDC25B(994), CDC25C(995)
相关类别
Biochem/physiol Actions
不可逆Cdc25双特异性磷酸酶抑制剂。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Qin Zhou et al.
PloS one, 5(10), e13538-e13538 (2010-11-05)
Keratin polypeptide 19 (K19) is a type I intermediate filament protein that is expressed in stratified and simple-type epithelia. Although K19 is known to be phosphorylated on tyrosine residue(s), conclusive site-specific characterization of these residue(s) and identification potential kinases that
Lei Jin et al.
Communications biology, 3(1), 349-349 (2020-07-06)
Angiogenesis is required for tissue repair; but abnormal angiogenesis or neovascularization (NV) causes diseases in the eye. The avascular status in the cornea is a prerequisite for corneal clarity and thought to be maintained by the equilibrium between proangiogenic and
Hong Li et al.
International journal of biological sciences, 16(7), 1107-1120 (2020-03-17)
Traumatic brain injury (TBI) induces an acute inflammatory response in the central nervous system that involves both resident and peripheral immune cells. The ensuing chronic neuroinflammation causes cell death and tissue damage and may contribute to neurodegeneration. The molecular mechanisms
Guan-Hao Zhao et al.
Biochemical pharmacology, 172, 113741-113741 (2019-12-10)
Na+/K+-ATPase α1 was reported to directly interact with and recruit FGF2 (fibroblast growth factor 2), a vital cell signaling protein implicated in angiogenesis, to the inner plasma membrane for subsequent secretion. Cardenolides, a class of cardiac glycosides, were reported to
Yan Han et al.
Journal of proteome research, 17(1), 579-589 (2017-12-21)
The new strategy for chemical toxicity testing and modeling is to use in vitro human cell-based assays in conjunction with quantitative high-throughput screening (qHTS) technology, to identify molecular mechanisms and predict in vivo responses. Stem cells are more physiologically relevant
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