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N193

1-Naphthylacetyl spermine trihydrochloride

Name: 1-Naphthylacetyl spermine trihydrochloride
Brand: SIGMA

≥95% (HPLC), Ca2+ permeable AMPA receptor channel blocker, powder

别名:

NASPM trihydrochloride

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关于此项目

经验公式（希尔记法）:

C₂₂H₃₄N₄O · 3HCl

化学文摘社编号:

1049731-36-3

分子量:

479.91

UNSPSC Code:

12352200

PubChem Substance ID:

24897539

NACRES:

NA.77

MDL number:

MFCD01321052

Assay:

≥95% (HPLC)

Form:

powder

Storage condition:

desiccated, protect from light

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属性

产品名称

1-Naphthylacetyl spermine trihydrochloride,

assay

≥95% (HPLC)

Quality Segment

100

form

powder

storage condition

desiccated, protect from light

color

white

solubility

H₂O: ≥20 mg/mL

SMILES string

Cl.Cl.Cl.NCCCNCCCCNCCCNC(=O)Cc1cccc2ccccc12

InChI

1S/C22H34N4O.3ClH/c23-12-6-15-24-13-3-4-14-25-16-7-17-26-22(27)18-20-10-5-9-19-8-1-2-11-21(19)20;;;/h1-2,5,8-11,24-25H,3-4,6-7,12-18,23H2,(H,26,27);3*1H

InChI key

JNEOJAUJWOPWJS-UHFFFAOYSA-N

说明

Application

1-Naphthylacetyl spermine trihydrochloride has been used for the inhibition of calcium-permeable AMPAR (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor). It has also been used to study the involvement of AMPAR in biphasic activation of stress-activated protein kinase/extracellular signal-regulated kinase-1.

Biochem/physiol Actions

Blocks Ca²⁺ permeable AMPA receptor channels.

Other Notes

Synthetic analog of Joro spider toxin.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c