Merck
CN

N3139

Sigma-Aldrich

β-烟酰胺腺嘌呤二核苷酸磷酸 水合物

powder, BioReagent, suitable for cell culture

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别名:
三磷酸吡啶核苷酸 钠盐 水合物
Empirical Formula (Hill Notation):
C21H27N7NaO17P3 · xH2O
分子量:
765.39 (anhydrous basis)
MDL编号:
PubChem化学物质编号:

产品线

BioReagent

质量水平

检测方案

≥98% (HPLC)
≥98% (spectrophotometric assay)

形式

powder

technique(s)

cell culture | mammalian: suitable

mp

175-178 °C (dec.) (lit.)

溶解性

H2O: 50 mg/mL

储存温度

−20°C

SMILES string

O[C@H]1[C@@H](O)[C@H]([N+]2=CC(C(N)=O)=CC=C2)O[C@@H]1COP(OP(OC[C@H]3O[C@@H](N(C=N4)C5=C4C(N)=NC=N5)[C@H](OP(O)(O)=O)[C@@H]3O)([O-])=O)([O-])=O.O.[Na+]

InChI

1S/C21H28N7O17P3.Na.H2O/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39);;1H2/q;+1;/p-1/t10-,11-,13-,14-,15-,16-,20-,21-;;/m1../s1

InChI key

CYQLUFJYVTUUFN-WUEGHLCSSA-M

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此商品
N0505N3886N7505
form

powder

form

powder

form

powder

form

powder

solubility

H2O: 50 mg/mL

solubility

H2O: soluble 50 mg/mL, clear, colorless to faintly yellow

solubility

-

solubility

10 mM NaOH: soluble 50 mg/mL, clear

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

product line

BioReagent

product line

-

product line

-

product line

-

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

-

technique(s)

-

应用

β-Nicotinamide adenine dinucleotide phosphate sodium salt hydrate has been used in the purification and crystallization of CHORD–Sgt1 cytochrome b 5 reductases (CS–b5R). It has also been used as a supplement in Dulbecco′s modified Eagle′s medium (DMEM)/F-12 medium for direct hepatic reprogramming using mouse embryonic fibroblasts (MEFs).

生化/生理作用

Nicotinamide adenine dinucleotide phosphate (NADP) is an indispensable cofactor that participates in cellular redox reactions. It acts as a hydride-accepting coenzyme and participates in substrate oxidation reactions during metabolism.
电子受体

包装

根据固体质量包装。

分析说明

Meets or exceeds NRC specifications and is comparable to any commercial preparation available.

其他说明

这是 NADP 的常见形式。不要与 3′-NADP 或 α-NADP 混淆。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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David R Benson et al.
Acta crystallographica. Section D, Structural biology, 75(Pt 7), 628-638 (2019-07-10)
Ncb5or (NADH-cytochrome b5 oxidoreductase), a cytosolic ferric reductase implicated in diabetes and neurological diseases, comprises three distinct domains, cytochrome b5 (b5) and cytochrome b5 reductase (b5R) domains separated by a CHORD-Sgt1 (CS) domain, and a novel 50-residue N-terminal region. Understanding

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