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N3510

氯硝柳胺

Name: 氯硝柳胺
Brand: SIGMA

别名:

2′,5-二氯-4′-硝基水杨酸酰替苯胺

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关于此项目

经验公式（希尔记法）:

C₁₃H₈Cl₂N₂O₄

化学文摘社编号:

50-65-7

分子量:

327.12

UNSPSC Code:

51102829

NACRES:

NA.85

PubChem Substance ID:

24278585

EC Number:

200-056-8

Beilstein/REAXYS Number:

2820605

MDL number:

MFCD00057597

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form

powder

Quality Level

200

antibiotic activity spectrum

parasites

mode of action

enzyme | inhibits

SMILES string

Oc1ccc(Cl)cc1C(=O)Nc2ccc(cc2Cl)[N+]([O-])=O

InChI

1S/C13H8Cl2N2O4/c14-7-1-4-12(18)9(5-7)13(19)16-11-3-2-8(17(20)21)6-10(11)15/h1-6,18H,(H,16,19)

InChI key

RJMUSRYZPJIFPJ-UHFFFAOYSA-N

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Application

氯硝柳胺是驱虫药系列中的特尼酰胺。它能帮助感染人有效对抗绦虫。氯硝柳胺用于研究Wnt / Frizzled-1信号传导途径。它用于抑制NF-κB转录和DNA结合，并提高ROS水平，诱导急性髓性白血病（AML）细胞凋亡。

Biochem/physiol Actions

氯硝柳胺解偶联绦虫氧化磷酸化，抑制寄生蠕虫线粒体氧化磷酸化。它阻断肿瘤坏死因子诱导的 IκBα 磷酸化、p65 的转位和 AML 细胞中 NF-κβ 调节基因的表达。

Other Notes

50g及250g

将容器密闭保存在干燥和通风良好的地方。在干燥处保存。

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

农药列管产品

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

0000517053

0000453974

0000359873

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Jing-Xuan Pan et al.

Chinese journal of cancer, 31(4), 178-184 (2012-01-13)

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全球贸易项目编号

货号	GTIN
N3510-250G	04061832991672
N3510-50G	04061834116141

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