应用
Neuraminidase is a glycoside hydrolase enzyme that is involved in the spread of the influenza virus. It is used to research potential drugs, such as neuraminidase inhibitors, to treat influenza. Neuraminidase mutations are studied for their implications on influenza drug resistance .
生化/生理作用
Neuraminidase cleaves the glycosidic linkages of neuraminic acids. Neuraminidase aids in the dispersment of the flu virus in mucosal secretions of the respiratory tract. It also prevents virions from self-aggregation .
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
In vitro passaging of a pandemic H1N1/09 virus selects for viruses with neuraminidase mutations conferring high-level resistance to oseltamivir and peramivir, but not to zanamivir
Jennifer L. McKimm-Breschkin, et al.
The Journal of Antimicrobial Chemotherapy, 10.1093, 150-150 (2012)
Larisa V Gubareva
Virus research, 103(1-2), 199-203 (2004-05-28)
A wide use of inhibitors of influenza virus neuraminidase (NAIs) to control influenza in humans demands a better understanding of the mechanisms involved in the resistance emergence. In vitro studies demonstrate that both neuraminidase (NA) and hemagglutinin (HA) influence virus
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