N3877
4-硝基苯硫酸钾
sulfatase substrate, chromogenic, ≥98% (TLC), powder
别名:
4-硝基苯硫酸盐 钾盐
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关于此项目
线性分子式:
NO2C6H4OSO2OK
化学文摘社编号:
分子量:
257.26
Beilstein:
3786392
EC 号:
MDL编号:
UNSPSC代码:
12352204
PubChem化学物质编号:
NACRES:
NA.32
产品名称
4-硝基苯硫酸钾, sulfatase substrate
方案
≥98% (TLC)
表单
powder
mp
246-250 °C (lit.)
溶解性
water: 50 mg/mL, clear, colorless to very faintly greenish-yellow (to Very Light Yellow)
运输
wet ice
储存温度
−20°C
SMILES字符串
[K+].[O-][N+](=O)c1ccc(OS([O-])(=O)=O)cc1
InChI
1S/C6H5NO6S.K/c8-7(9)5-1-3-6(4-2-5)13-14(10,11)12;/h1-4H,(H,10,11,12);/q;+1/p-1
InChI key
BITVAZYUWRLLCN-UHFFFAOYSA-M
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一般描述
显色硫酸酯酶底物。
应用
4-硝基苯基硫酸钾已用于：
- 作为底物，测定无细胞体腔液中芳基硫酸酯酶的活性
- 作为基于p-硝基苯基糖苷的酶分析的底物
- ，抑制芳基硫酸酯酶
- 作为有机芳基酯硫酸酯的无机类似物
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
M P Kung et al.
Endocrinology, 122(4), 1195-1200 (1988-04-01)
Subcellular preparations from rat liver, brain, and kidney and from human liver were tested for their ability to desulfate T3 sulfate (T3SO4). Activity was found associated with the microsomal fraction: rat liver was the most active, hydrolyzing 76 pmol/min.mg protein
H X Zhang et al.
Drug metabolism and disposition: the biological fate of chemicals, 19(2), 473-477 (1991-03-01)
Although numerous previous reports have characterized the mammalian biotransformation of the organophosphorus insecticides parathion and methyl parathion, questions still remain regarding the toxicological significance of certain metabolic pathways in vivo. The present study utilized rat liver perfusions in order to
J O Falkinham
International journal of systematic bacteriology, 40(1), 66-70 (1990-01-01)
A rapid (3-h) arylsulfatase assay for cell suspensions of mycobacteria, in which p-nitrophenyl sulfate is used as the substrate, was developed. Arylsulfatase activity was found in cell suspensions of representative strains of Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium scrofulaceum grown
N Sakuma-Sawada et al.
Research communications in molecular pathology and pharmacology, 97(2), 131-138 (1997-08-01)
Hepatic uptake of the sulfate conjugate of p-nitrophenol (p-NPsul) has been studied. Uptake clearance of p-NPsul by isolated rat hepatocytes was dependent on p-NPsul concentration, suggesting carrier-mediated transport. The uptake of p-NPsul by isolated rat hepatocytes was inhibited by acetaminophen
J-H Kim et al.
Applied microbiology and biotechnology, 63(5), 553-559 (2003-11-06)
Arylsulfatase was purified from Sphingomonas sp. AS6330 through ionic exchange, hydrophobic- and gel-chromatographies. The purity increased 12,800-fold with approximately 19.1% yield against cell homogenate. The enzyme was a monomeric protein with apparent molecular weight of 62 kDa as determined by
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