Merck
CN

N3877

Sigma-Aldrich

4-硝基苯硫酸钾

sulfatase substrate

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别名:
4-硝基苯硫酸盐 钾盐
线性分子式:
NO2C6H4OSO2OK
CAS号:
分子量:
257.26
Beilstein:
3786392
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.32

质量水平

检测方案

≥98% (TLC)

形式

powder

mp

246-250 °C (lit.)

溶解性

water: 50 mg/mL, clear, colorless to very faintly greenish-yellow (to Very Light Yellow)

运输

wet ice

储存温度

−20°C

SMILES string

[K+].[O-][N+](=O)c1ccc(OS([O-])(=O)=O)cc1

InChI

1S/C6H5NO6S.K/c8-7(9)5-1-3-6(4-2-5)13-14(10,11)12;/h1-4H,(H,10,11,12);/q;+1/p-1

InChI key

BITVAZYUWRLLCN-UHFFFAOYSA-M

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应用

4-硝基苯基硫酸钾已用于:
  • 作为底物,测定无细胞体腔液中芳基硫酸酯酶的活性
  • 作为基于p-硝基苯基糖苷的酶分析的底物
  • ,抑制芳基硫酸酯酶
  • 作为有机芳基酯硫酸酯的无机类似物

底物

显色硫酸酯酶底物。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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N Sakuma-Sawada et al.
Research communications in molecular pathology and pharmacology, 97(2), 131-138 (1997-08-01)
Hepatic uptake of the sulfate conjugate of p-nitrophenol (p-NPsul) has been studied. Uptake clearance of p-NPsul by isolated rat hepatocytes was dependent on p-NPsul concentration, suggesting carrier-mediated transport. The uptake of p-NPsul by isolated rat hepatocytes was inhibited by acetaminophen
J O Falkinham
International journal of systematic bacteriology, 40(1), 66-70 (1990-01-01)
A rapid (3-h) arylsulfatase assay for cell suspensions of mycobacteria, in which p-nitrophenyl sulfate is used as the substrate, was developed. Arylsulfatase activity was found in cell suspensions of representative strains of Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium scrofulaceum grown
M P Kung et al.
Endocrinology, 122(4), 1195-1200 (1988-04-01)
Subcellular preparations from rat liver, brain, and kidney and from human liver were tested for their ability to desulfate T3 sulfate (T3SO4). Activity was found associated with the microsomal fraction: rat liver was the most active, hydrolyzing 76 pmol/min.mg protein
H X Zhang et al.
Drug metabolism and disposition: the biological fate of chemicals, 19(2), 473-477 (1991-03-01)
Although numerous previous reports have characterized the mammalian biotransformation of the organophosphorus insecticides parathion and methyl parathion, questions still remain regarding the toxicological significance of certain metabolic pathways in vivo. The present study utilized rat liver perfusions in order to
Proteomic profiles reveal age-related changes in coelomic fluid of sea urchin species with different life spans
Bodnar A
Experimental Gerontology, 48(5), 525-530 (2013)

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