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Merck
CN

N3915

Sigma-Aldrich

三七皂苷R1

≥98% (HPLC)

别名:

(3β,6α,12β)-20-(β-D-葡糖基核糖氧基)-3,12-二羟基达玛-24-en-6-yl 2-O-β-D-木吡喃糖基-β-D-吡喃葡萄糖苷, 人参皂苷R1

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关于此项目

经验公式（希尔记法）:
C47H80O18
CAS Number:
80418-24-2
分子量:
933.13
MDL编号:
MFCD00210535
UNSPSC代码:
12352205
PubChem化学物质编号:
329818642
NACRES:
NA.25

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生物来源

Panax notoginseng (Burk.) F.H.Chen

质量水平

100

方案

≥98% (HPLC)

表单

powder

颜色

white to off-white

溶解性

H2O: 1 mg/mL, clear, colorless

应用

metabolomics
vitamins, nutraceuticals, and natural products

储存温度

2-8°C

SMILES字符串

C\C(C)=C\CC[C@](C)(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H]2CC[C@]3(C)[C@@H]2[C@H](O)C[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5[C@H](C[C@@]34C)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O[C@@H]7OC[C@@H](O)[C@H](O)[C@H]7O

InChI

1S/C47H80O18/c1-21(2)10-9-13-47(8,65-41-37(59)34(56)32(54)26(18-48)62-41)22-11-15-45(6)30(22)23(50)16-28-44(5)14-12-29(52)43(3,4)39(44)25(17-46(28,45)7)61-42-38(35(57)33(55)27(19-49)63-42)64-40-36(58)31(53)24(51)20-60-40/h10,22-42,48-59H,9,11-20H2,1-8H3/t22-,23+,24+,25-,26+,27+,28+,29-,30-,31-,32+,33+,34-,35-,36+,37+,38+,39-,40-,41-,42+,44+,45+,46+,47-/m0/s1

InChI key

LLPWNQMSUYAGQI-OOSPGMBYSA-N

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相关类别

生化/生理作用

三七皂苷R1已显示出具有抗氧化剂、抗炎、抗凋亡和免疫刺激特性。

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H302

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCT6751
MKBW8373V
SLBB0147V

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ZhiGuo Yu et al.
Chemical & pharmaceutical bulletin, 54(4), 588-590 (2006-04-06)
A high-performance liquid chromatograph with mass spectrum detection (HPLC-MS/APCI) method has been established for simultaneous determination of ten major bioactive components of Naodesheng injection including safflor yellow A, puerarin, daidzein, ginsenosides (Rg1, Rg2, Rb1, Rd, Re, Rh1), and notoginsenoside R1.
Chong Li et al.
American journal of physiology. Gastrointestinal and liver physiology, 306(2), G111-G122 (2013-11-16)
Intestinal ischemia and reperfusion (I/R) is a clinical problem occurred for diverse causes with high mortality. Prophylaxis and treatment of intestinal I/R remains a challenge for clinicians. The purpose of the present study was to explore the role of Notoginsenoside
J B Wan et al.
Journal of pharmaceutical and biomedical analysis, 41(1), 274-279 (2005-12-01)
A HPLC and pressurized liquid extraction (PLE) method was developed for simultaneous determination of nine saponins, including notoginsenoside R1, ginsenoside Rg1, Re, Rf, Rb1, Rc, Rb2, Rb3 and Rd in Panax notoginseng. The analysis was performed on C18 column with
Hong-Sheng Zhang et al.
Vascular pharmacology, 44(4), 224-230 (2006-02-07)
Notoginsenoside R1 is the main ingredient with cardiovascular activity in Panax notoginseng. We reported that notoginsenoside R1 significantly decreased tumor necrosis factor-alpha (TNF-alpha)-induced plasminogen activator inhibitor-1 (PAI-1) mRNA, protein level and secretion in human aortic smooth muscle cells (HASMCs) in
Shan Cong et al.
International immunopharmacology, 68, 137-144 (2019-01-10)
Pneumonia is a common lung disease in children with high fatality rate. Notoginsenoside R1 (NGR1) is the main active component extracted from the roots of Panax notoginseng (Burk.) F.H. Chen (Araliaceae). Here, we carefully explored the potential anti-inflammatory and protective
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