N4159
NCS-382 hydrate
solid, ≥98% (HPLC)
别名:
5,7,8,9-Tetrahydro-5-hydroxy-6H-benzocyclohepten-6-ylidene acetic acid monosodium salt hydrate
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关于此项目
经验公式（希尔记法）:
C13H13O3Na · xH2O
化学文摘社编号:
分子量:
240.23 (anhydrous basis)
UNSPSC Code:
12352202
PubChem Substance ID:
MDL number:
InChI
1S/C13H14O3.Na.H2O/c14-12(15)8-10-6-3-5-9-4-1-2-7-11(9)13(10)16;;/h1-2,4,7-8,13,16H,3,5-6H2,(H,14,15);;1H2/q;+1;/p-1/b10-8+;;
SMILES string
O.[Na+].OC1C(\CCCc2ccccc12)=C\C([O-])=O
InChI key
FCHWTCFJPQOCCJ-PIHABLKOSA-M
assay
≥98% (HPLC)
form
solid
color
white to off-white
solubility
H2O: 22 mg/mL
Quality Level
Biochem/physiol Actions
γ-Hydroxybutyrate (GHB) receptor antagonist; anticonvulsant.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
M Maitre et al.
The Journal of pharmacology and experimental therapeutics, 255(2), 657-663 (1990-11-01)
Administration of gamma-hydroxybutyrate (GHB) to animals induces electroencephalographic and behavioral changes that resemble petit-mal seizures. Furthermore, these GHB-induced electroencephalogram-behavioral changes can be blocked by anticonvulsant drugs, which are specific in their action against petit-mal seizures. These effects of GHB on
M Maitre
Progress in neurobiology, 51(3), 337-361 (1997-02-01)
gamma-Hydroxybutyrate is a metabolite of GABA which is synthesized and accumulated by neurons in brain. This substance is present in micromolar quantities in all brain regions investigated as well as in several peripheral organs. Neuronal depolarization releases gamma-hydroxybutyrate into the
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