N4286
NU2058
>98% (HPLC)
别名:
O6-Cyclohexylmethylguanine
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关于此项目
经验公式（希尔记法）:
C12H17N5O
化学文摘社编号:
分子量:
247.30
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
产品名称
NU2058, >98% (HPLC)
InChI key
MWGXGTJJAOZBNW-UHFFFAOYSA-N
SMILES string
Nc1nc(OCC2CCCCC2)c3nc[nH]c3n1
InChI
1S/C12H17N5O/c13-12-16-10-9(14-7-15-10)11(17-12)18-6-8-4-2-1-3-5-8/h7-8H,1-6H2,(H3,13,14,15,16,17)
assay
>98% (HPLC)
form
solid
color
white
solubility
DMSO: 22 mg/mL
H2O: soluble
storage temp.
2-8°C
Quality Level
Gene Information
human ... CDK2(1017)
Biochem/physiol Actions
Selective cyclin-dependent kinase-2 (CDK2) inhibitor.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Evgenia Lampropoulou et al.
Scientific reports, 8(1), 5893-5893 (2018-04-14)
Pleiotrophin (PTN) stimulates endothelial cell migration through binding to receptor protein tyrosine phosphatase beta/zeta (RPTPβ/ζ) and ανβ3 integrin. Screening for proteins that interact with RPTPβ/ζ and potentially regulate PTN signaling, through mass spectrometry analysis, identified cyclin-dependent kinase 5 (CDK5) activator
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