Anti-NAV3 (C-terminal) 兔抗

NAV3 belongs to the neuron navigator (NAV) family of proteins. NAV3 is expressed in adult heart, kidney, and brain.

Neuron navigator 3 (NAV3) is highly expressed in tumors. It possesses actin-binding domains and the gene encoding it is localized on chromosome 12q21.

Anti-NAV3 (C-terminal) antibody has been used in immunoblotting, western blotting.

NAV3 has been suggested to function as a novel tumor suppressor gene. Deletions and translocation affecting NAV3 have been shown to occur in patients with advanced mycosis fungoides or Sézary syndrome, the most common forms of primary cutaneous T-cell lymphoma (CTCL).

Neuron navigator 3 (NAV3) has been shown to control migration and invasion of epithelial cells. Once it is activated by growth factors, NAV3 occupies the ends of microtubules and stimulates their growth.

0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。

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