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Merck
CN

N4766

N-亚硝基-N-甲基脲

Bulk package

别名:

MNU, N-甲基-N-亚硝基脲

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关于此项目

经验公式(希尔记法):
C2H5N3O2
化学文摘社编号:
分子量:
103.08
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
Form:
solid
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form

solid

contains

aqueous acetic acid as stabilizer

storage temp.

2-8°C

SMILES string

CN(N=O)C(N)=O

InChI

1S/C2H5N3O2/c1-5(4-7)2(3)6/h1H3,(H2,3,6)

InChI key

ZRKWMRDKSOPRRS-UHFFFAOYSA-N

Biochem/physiol Actions

一种在许多动物物种中具有致癌性的DNA烷基化剂。 尽管MNU可以在大多数器官中诱发良性和恶性肿瘤,但它最常用于模拟乳腺肿瘤的发生和发展。

Packaging

Weight on dry basis.


signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Carc. 1B - Flam. Sol. 2 - Repr. 1B

存储类别

4.1B - Flammable solid hazardous materials

wgk

WGK 1

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges, type P3 (EN 143) respirator cartridges

法规信息

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Marzena Kurowska et al.
Mutation research, 738-739, 52-70 (2012-10-23)
We present studies aimed at determining the types and frequencies of mutations induced in the barley genome after treatment with chemical (N-methyl-N-nitrosourea, MNU) and physical (gamma rays) mutagens. We created M(2) populations of a doubled haploid line and used them
Kawiya Sintara et al.
Journal of biomedicine & biotechnology, 2012, 915380-915380 (2012-06-13)
To determine effects of curcumin on N-methyl-N-nitrosourea (MNU) and saturated sodium chloride (s-NaCl)-induced gastric cancer in rats. Male Wistar rats were divided into 5 groups: control (CO), control supplemented with 200 mg/kg curcumin (CC), MNU + s-NaCl, MNU + s-NaCl supplemented with 200 mg/kg curcumin daily
Yuan-Yuan Chen et al.
Experimental eye research, 121, 102-113 (2014-02-11)
Mouse retinal degeneration models have been investigated for many years in the hope of understanding the mechanism of photoreceptor cell death. N -methyl- N -nitrosourea (MNU) has been previously shown to induce outer retinal degeneration in mice. After MNU was