N4773
神经元特异性烯醇化酶 来源于人类大脑
≥95% (SDS-PAGE), buffered aqueous solution
别名:
2-磷酸-D-甘油酸水解酶, NSE, 不耐热抗原A, 烯醇化酶，神经元特异性 来源于人类大脑
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关于此项目
Specific activity:
≥10 units/mg protein
Assay:
≥95% (SDS-PAGE)
Biological source:
human brain
biological source
human brain
assay
≥95% (SDS-PAGE)
form
buffered aqueous solution
specific activity
≥10 units/mg protein
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Quality Level
Gene Information
human ... ENO2(2026)
General description
神经元特异性烯醇化酶(NSE)是糖酵解酶烯醇化酶的神经元形式，首先在脑组织提取物中发现。
Application
来自人脑的神经元特异性烯醇化酶已用于评估人羊膜间充质干细胞治疗局灶性脑缺血的研究。 它也被用于研究具有横纹肌样特征的鼻窦畸胎癌肉瘤。
Biochem/physiol Actions
神经元特异性烯醇化酶(NSE)在所有神经元细胞类型中表达，其表达标志着突触功能的获得。 急性神经元损伤后，神经元细胞体中的NSE水平升高。 血清和脑脊液中NSE水平的升高已被用作损伤和神经元细胞死亡的标志物。 源自许多细胞类型的肿瘤，包括大多数神经元和神经内分泌肿瘤，都表达NSE。
神经元特异性烯醇化酶促进神经元的存活，并可以通过以钙依赖性方式与神经元结合来提供神经保护作用。
Physical form
溶液，溶于100 mM Tris-HCl、5 mM MgSO4、250 mM KCl，pH 5.0-5.2
Other Notes
25°C，pH 6.8时，1个单位每分钟形成1.0μ摩尔磷酸（烯醇）丙酮酸盐
存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
高风险级别生物产品--人源产品
此项目有
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