N5415
神经生长因子-β 人
≥95% (SDS-PAGE), recombinant, expressed in HEK 293 cells, lyophilized powder, suitable for cell culture
别名:
β-NGF, BNGF, NGF-β
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UNSPSC Code:
12352202
NACRES:
NA.77
Biological source:
human
Recombinant:
expressed in HEK 293 cells
Assay:
≥95% (SDS-PAGE)
Form:
lyophilized powder
Mol wt:
protein calculated mol wt 13.5 kDa (Monomer)
Impurities:
≤1 EU/μg Endotoxin (β-NGF)
产品名称
神经生长因子-β 人, recombinant, expressed in HEK 293 cells, lyophilized powder, suitable for cell culture
biological source
human
recombinant
expressed in HEK 293 cells
assay
≥95% (SDS-PAGE)
form
lyophilized powder
potency
≤16 ng/mL ED50/EC50
mol wt
protein calculated mol wt 13.5 kDa (Monomer)
packaging
pkg of 10 μg, pkg of 100 μg
technique(s)
cell culture | mammalian: suitable
impurities
≤1 EU/μg Endotoxin (β-NGF)
UniProt accession no.
storage temp.
−20°C
Quality Level
Gene Information
human ... NGF(4803)
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General description
NGF-β基因定位于人类染色体1p13.2。
重组人β-NGF在人293细胞中以120个氨基酸的同型二聚体（非二硫键）表达，计算分子量为13.5 kDa（单体）。神经生长因子β（β-NGF）是一种在结构上与BDNF、NT-3和NT-4相关的神经营养因子。天然β-NGF的产生发生在上皮细胞和脑下垂体中。
Biochem/physiol Actions
NGF-β基因的突变与疼痛感的丧失有关。
神经生长因子β（β-NGF）是一种有效的神经营养因子，通过其受体β-NGFR发出信号，在感觉和交感神经系统的发育和保存中起着至关重要的作用。β-NGF促进基底前脑胆碱能神经元的存活和胆碱能表型，并在体外刺激胚胎三叉神经运动神经元的神经突向外生长。
Physical form
该产品从PBS中冻干获得。
Preparation Note
将产品储存在-20°C下。产品在供应时可保持至少2年的活性。初始解冻后，建议将蛋白以工作等分试样储存在-20 °C下。
打开前短暂离心小瓶。 建议在含有0.1%无内毒素重组人血清白蛋白的无菌DDW中复溶蛋白质，使其最终浓度为100 μg/mL。
Analysis Note
通过人TF-1细胞（人红白血病指示细胞系）增殖的剂量依赖性刺激测定比活性。
Disclaimer
产品在供应时可保持至少2年的活性。 初始解冻后，建议将蛋白以工作等分试样储存在-20℃下。
除非我们的目录中另有说明，否则我们的产品预期仅用于研究用途，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或对人类或动物的任何类型的消费或应用。
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
wgk
WGK 1
法规信息
监管及禁止进口产品
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