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安全信息

N6252

Sigma-Aldrich

去甲哈尔满

≥98% (TLC), crystalline, monoamine oxidase inhibitor

别名:

β-咔啉, 9H-吡啶并[3,4-b]吲哚

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1 ML
¥5,628.16

About This Item

经验公式(希尔记法):
C11H8N2
CAS Number:
分子量:
168.19
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77

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Product Name

去甲哈尔满, crystalline

表单

crystalline

质量水平

颜色

light yellow

储存温度

2-8°C

SMILES字符串

c1ccc2c(c1)[nH]c3cnccc23

InChI

1S/C11H8N2/c1-2-4-10-8(3-1)9-5-6-12-7-11(9)13-10/h1-7,13H

InChI key

AIFRHYZBTHREPW-UHFFFAOYSA-N

基因信息

human ... IKBKB(3551)
rat ... Gabra2(29706)

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此商品
S144SMB0031139303
Shogaol ≥90% (HPLC)

SMB00311

Shogaol

[6]-Shogaol analytical standard

39303

[6]-Shogaol

grade

certified reference material

grade

certified reference material

grade

-

grade

analytical standard

format

multi-component solution

format

multi-component solution

format

-

format

neat

feature

Snap-N-Spike®/Snap-N-Shoot®

feature

Snap-N-Spike®/Snap-N-Shoot®

feature

-

feature

-

composition

6-Gingerol, 500 μg/mL

composition

Isosilybin, 200 μg/mL , Silybin, 200 μg/mL , Silychristin, 200 μg/mL , Silydianin, 200 μg/mL , Taxifolin
Taxifolin, 200 μg/mL

composition

-

composition

-

packaging

ampule of 1 mL

packaging

ampule of 1 mL

packaging

-

packaging

-

manufacturer/tradename

Cerilliant®

manufacturer/tradename

Cerilliant®

manufacturer/tradename

-

manufacturer/tradename

-

一般描述

Norharmane is an alkaloid widely present in living organisms and can also be chemically synthesized. It is a β-carboline derivative composed of indole and pyridine.

应用

Norharmane has been used:
  • as a β-carboline to study its effect on nigrostriatal dopamine (DA) neurons
  • as an internal standard in gas chromatography-mass spectrometry (GC-MS) analyses using Conidiobulus coronatus filtrates
  • as a β-carboline-3-carboxylic acid N-methylamide (CMA) analog to study its binding ability with Mcm2-7 (minichromosome maintenance)

生化/生理作用

吲哚胺 2,3-双加氧酶 (IDO) 的抑制剂。
Norharmane and its derivative exhibit anti-cancer properties. It acts as a monoamine oxidase (MAO) inhibitor and might benefit Parkinson′s disease (PD). High levels of β-carboline in plasma are found in PD.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

危险化学品

  • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number

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