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Merck
CN

N6664

神经连氮

≥98% (HPLC)

别名:

2-[5-(3-Chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H imidazole

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关于此项目

经验公式(希尔记法):
C27H21ClN2O3
化学文摘社编号:
分子量:
456.92
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352203
MDL number:
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产品名称

神经连氮, ≥98% (HPLC)

InChI key

FEEOFPAEDSMOTO-UHFFFAOYSA-N

SMILES string

COc1ccc(cc1)-c2nc([nH]c2-c3ccc(OC)cc3)-c4ccc(o4)-c5cccc(Cl)c5

InChI

1S/C27H21ClN2O3/c1-31-21-10-6-17(7-11-21)25-26(18-8-12-22(32-2)13-9-18)30-27(29-25)24-15-14-23(33-24)19-4-3-5-20(28)16-19/h3-16H,1-2H3,(H,29,30)

assay

≥98% (HPLC)

form

powder

color

yellow

solubility

DMSO: >20 mg/mL

storage temp.

−20°C

Quality Level

Biochem/physiol Actions

Neurodazine is a promoter of neurogenesis. It induces a generation of new nerve cells from skeletal muscle fibers both immature, differentiated myotubes and mature skeletal muscle. Neurodazine promotes the expression of neuron-specific markers in treated C2C12 cells (neurogenesis). In addition, in conjunction with a microtubule-destabilizing agent, Neurodazine allows neurogenic conversion of both differentiated immature myotubes and mature skeletal muscle. Neurodazine is a potential alternative approach to using stem cells.
Neurodazine is a promoter of neurogenesis; induces generation of new nerve cells from skeletal muscle fibers both immature differentiated myotubes and mature skeletal muscle; a potential alternative approach to using stem cells.

pictograms

Skull and crossbonesCorrosion

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 4 - Eye Dam. 1

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jun Ding et al.
Journal of Alzheimer's disease : JAD, 37(3), 587-592 (2013-08-21)
Ciliary neurotrophic factor (CNTF) is a pleiotropic cytokine that has been fully studied for its structure, receptor, and signaling pathways and its multiplex effects on neural system, skeletal muscle, and weight control. Recent research demonstrates that CNTF also plays an
Ronald W Irwin et al.
Frontiers in endocrinology, 2, 117-117 (2011-01-01)
The proliferative pool and regenerative potential of neural stem cells diminishes with age, a phenomenon that may be exacerbated in prodromal and mild Alzheimer's disease (AD) brains. In parallel, the neuroactive progesterone metabolite, allopregnanolone (APα), along with a host of

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