N6756
烟酰胺核苷酸次黄嘌呤，还原形式 钠盐
Grade I, ≥95%
别名:
烟酰胺次黄嘌呤二核苷酸，还原形式, 脱氨基 DPNH, 脱氨基NADH
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选择尺寸
关于此项目
经验公式（希尔记法）:
C21H28N6O15P2 · xNa+
分子量:
666.43 (free acid basis)
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
MDL number:
产品名称
烟酰胺核苷酸次黄嘌呤，还原形式 钠盐, Grade I, ≥95%
InChI
1S/C21H28N6O15P2/c22-17(32)9-2-1-3-26(4-9)20-15(30)13(28)10(40-20)5-38-43(34,35)42-44(36,37)39-6-11-14(29)16(31)21(41-11)27-8-25-12-18(27)23-7-24-19(12)33/h1,3-4,7-8,10-11,13-16,20-21,28-31H,2,5-6H2,(H2,22,32)(H,34,35)(H,36,37)(H,23,24,33)
SMILES string
NC(=O)C1=CN(C=CC1)C2OC(COP(O)(=O)OP(O)(=O)OCC3OC(C(O)C3O)n4cnc5C(=O)N=CNc45)C(O)C2O
InChI key
WXWNHSQIXJHVJY-UHFFFAOYSA-N
type
Grade I
assay
≥95%
form
powder
storage temp.
−20°C
Quality Level
Application
可以使用还原型烟酰胺次黄嘌呤二核苷酸（脱氨基-NADH）研究NADH:泛醌氧化还原酶的特异性和动力学。
Other Notes
β-NADH的类似物
Preparation Note
酶促还原。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Jiwon Kang et al.
Journal of biochemistry and molecular biology, 40(1), 53-57 (2007-01-25)
The enzymatic properties of NADH:quinone oxidoreductase were examined in Triton X-100 extracts of Bacillus cereus membranes by using the artificial electron acceptors ubiquinone-1 and menadione. Membranes were prepared from B. cereus KCTC 3674 grown aerobically on a complex medium and
Jukka Pätsi et al.
The Biochemical journal, 409(1), 129-137 (2007-09-27)
LHON (Leber hereditary optic neuropathy) is a maternally inherited disease that leads to sudden loss of central vision at a young age. There are three common primary LHON mutations, occurring at positions 3460, 11778 and 14484 in the human mtDNA
Rosa Pello et al.
Human molecular genetics, 17(24), 4001-4011 (2008-09-23)
Leber's hereditary optic neuropathy (LHON), the most frequent mitochondrial disorder, is mostly due to three mitochondrial DNA (mtDNA) mutations in respiratory chain complex I subunit genes: 3460/ND1, 11778/ND4 and 14484/ND6. Despite considerable clinical evidences, a genetic modifying role of the
Kenji Kawahara et al.
Journal of biochemistry, 145(2), 229-237 (2008-12-09)
In the intraerythrocytic stages of malaria parasites, mitochondria lack obvious cristae and are assumed to derive energy through glycolysis. For understanding of parasite energy metabolism in mammalian hosts, we isolated rodent malaria mitochondria from Plasmodium yoelii yoelii grown in mice.
Pilvi Maliniemi et al.
Mitochondrion, 9(6), 394-401 (2009-07-21)
Seven of the 45 subunits of mitochondrial NADH:ubiquinone oxidoreductase (complex I) are mitochondrially encoded and have been shown to harbor pathogenic mutations. We modeled the human disease-associated mutations A4136G/ND1-Y277C, T4160C/ND1-L285P and C4171A/ND1-L289M in a highly conserved region of the fourth
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