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Merck
CN

N7127

DL-去甲肾上腺素 盐酸盐

≥98%, Norepinephrine metabolite., powder

别名:

DL-α-(氨基甲基)-4-羟基-3-甲氧基苯甲醇 盐酸盐

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关于此项目

经验公式(希尔记法):
C9H13NO3 · HCl
化学文摘社编号:
分子量:
219.67
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
213-787-2
MDL number:
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产品名称

DL-去甲肾上腺素 盐酸盐, ≥98%

InChI

1S/C9H13NO3.ClH/c1-13-9-4-6(8(12)5-10)2-3-7(9)11;/h2-4,8,11-12H,5,10H2,1H3;1H

InChI key

VKFPRGQZWKTEON-UHFFFAOYSA-N

SMILES string

NCC(C1=CC(OC)=C(C=C1)O)O.Cl

assay

≥98%

form

powder

solubility

H2O: 50 mg/mL

Quality Level

Biochem/physiol Actions

去甲肾上腺素代谢产物。

pictograms

Exclamation mark

signalword

Warning

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1B

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M Tsunoda et al.
Analytical biochemistry, 269(2), 386-392 (1999-05-01)
A highly specific and sensitive automated high-performance liquid chromatographic method for the simultaneous determination of catecholamines (CAs; norepinephrine, epinephrine, and dopamine) and their 3-O-methyl metabolites (normetanephrine, metanephrine, and 3-methoxytyramine) is described. Automated precolumn ion-exchange extraction of diluted plasma is coupled
T Mano et al.
Thyroid : official journal of the American Thyroid Association, 8(4), 353-358 (1998-05-20)
Clinical and experimental data suggest that thyroid hormone affects the actions of catecholamine (CA). However, the serum or tissue levels of CA during thyroid disorders have not been well defined. Accordingly, we investigated the levels of CA and their metabolites
Jiamin Zheng et al.
Analytica chimica acta, 1037, 159-167 (2018-10-08)
A robust, sensitive, high-throughput method for the detection and quantification of catecholamines in serum, including dopamine, 5-methoxytryptamine, tyramine, phenylethylamine (PEA), epinephrine (EPI), norepinephrine (NE), metanephrine (MN), and normetanephrine (NMN) is described. It is based on liquid chromatography-tandem mass spectrometry (LC-MS/MS)
G Eisenhofer
Naunyn-Schmiedeberg's archives of pharmacology, 349(3), 259-269 (1994-03-01)
The importance of neuronal reuptake for terminating the actions of noradrenaline is well established, but the role of extraneuronal uptake is less clear. This study used plasma concentrations of the extraneuronal noradrenaline metabolite, normetanephrine, to estimate rates of extraneuronal removal
Riin Rebane et al.
European journal of mass spectrometry (Chichester, England), 26(1), 46-54 (2019-07-11)
Metanephrine and normetanephrine are measured in blood plasma to diagnose different diseases. Simpler sample preparation procedures are preferred but tend to yield less purified extracts. Therefore, thorough investigation of matrix effects is required. In this work, several sample preparation methods

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