N7287
NU-1025
≥97% (HPLC), solid
别名:
8-Hydroxy-2-methylquinazolin-4[3H]-one
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关于此项目
经验公式（希尔记法）:
C9H8N2O2
化学文摘社编号:
分子量:
176.17
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI key
YJDAOHJWLUNFLX-UHFFFAOYSA-N
SMILES string
CC1=Nc2c(O)cccc2C(=O)N1
InChI
1S/C9H8N2O2/c1-5-10-8-6(9(13)11-5)3-2-4-7(8)12/h2-4,12H,1H3,(H,10,11,13)
assay
≥97% (HPLC)
form
solid
color
off-white
solubility
DMSO: soluble >20 mg/mL, H2O: insoluble
storage temp.
−20°C
Quality Level
Gene Information
mouse ... Parp2(11546)
Biochem/physiol Actions
NU-1025 is a PARP inhibitor.
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
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Journal of cellular and molecular medicine, 24(18), 10420-10431 (2020-07-21)
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Molecular biology of the cell, 30(20), 2584-2597 (2019-08-08)
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Yang Sun et al.
American journal of respiratory cell and molecular biology, 51(6), 738-749 (2014-05-31)
Lymphangioleiomyomatosis (LAM) is a female-predominant cystic lung disease that can lead to respiratory failure. LAM cells typically have inactivating tuberous sclerosis complex 2 (TSC2) mutations and mammalian target of rapamycin (mTOR) complex (mTORC) 1 activation. Clinical response to the mTORC1
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